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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Endocrinology Research

Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.

Showing 41-50 of 217 results

AgingEndocrinology

Editorial: (Osteo)sarcopenia & sarcopenic obesity, volume II

Frontiers in Endocrinology, 2023 • November 6, 2023

This editorial summarizes findings from a research topic focused on (osteo)sarcopenia and sarcopenic obesity, highlighting the relationship between sarcopenia and various comorbidities such as obesity...

KEY FINDING: Obesity is a risk factor for sarcopenia, with a positive relationship between skeletal muscle mass and absolute fat mass but a negative association with appendicular fat mass.

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Spinal Cord InjuryPharmacologyEndocrinology

Salsalate Improves Postprandial Glycemic and Some Lipid Responses in Persons With Tetraplegia: A Randomized Clinical Pilot Trial With Crossover Design

Top Spinal Cord Inj Rehabil, 2023 • July 1, 2023

This study investigated the effects of salsalate on fasting and postprandial glycemic, lipidemic, and inflammatory responses in persons with tetraplegia. The main findings were that salsalate signific...

KEY FINDING: Salsalate significantly reduced fasting and postprandial glucose values in persons with tetraplegia.

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Spinal Cord InjuryEndocrinology

The effect of level of injury on diabetes incidence and mortality after spinal cord injury – a longitudinal cohort study

Spinal Cord, 2024 • April 1, 2024

This retrospective longitudinal cohort study examined the effect of the level of spinal cord injury (SCI) on the incidence of diabetes mellitus (DM) and mortality in a cohort of veterans. The study fo...

KEY FINDING: The risk of DM development over the 21-year follow-up period did not differ significantly between those with tetraplegia (TP) and paraplegia (PP).

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Spinal Cord InjuryEndocrinologyNutrition & Dietetics

Validation of basal metabolic rate equations in persons with innervated and denervated chronic spinal cord injury

Physiological Reports, 2024 • May 20, 2024

This study validated existing BMR prediction equations in individuals with SCI, focusing on innervated and denervated subgroups, and examined differences between predicted and measured BMR in females ...

KEY FINDING: SCI-­specific equations by Chun et  al., Nightingale & Gorgey, and AB-­specific FFM equations accurately predicted BMR for innervated males.

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EndocrinologyRehabilitationMusculoskeletal Medicine

Monthly treatment with romosozumab for 1 year increases bone mineral at the hip, but not the knee, in women with chronic spinal cord injury

JBMR Plus, 2024 • June 7, 2024

One year of romosozumab treatment in women with chronic SCI increased DXA-derived aBMD at the lumbar spine and hip. These results were congruent with CT results at the hip, which indicated increases i...

KEY FINDING: After 12 mo of treatment, areal BMD at the lumbar spine and total hip were significantly increased with median changes of 10.2% (IQR: 8.3–15.2%, p<.001) and 4.2% (IQR: 3.4–7.7%, p = .009), respectively.

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Spinal Cord InjuryEndocrinologyNeurology

Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons

Restor Neurol Neurosci, 2024 • February 25, 2024

This study examined the effects of exercise and hormone treatment on urinary dysfunction and EUS motoneuron morphology after SCI. Exercise improved locomotor performance but did not improve urinary fu...

KEY FINDING: Locomotor performance was improved in exercised animals after SCI.

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Spinal Cord InjuryEndocrinologyMusculoskeletal Medicine

Preventing OsteoPorosis in Spinal Cord Injury (POPSCI) Study—Early Zoledronic Acid Infusion in Patients with Acute Spinal Cord Injury

Calcified Tissue International, 2024 • September 25, 2024

This study evaluated the impact of early zoledronic acid (ZOL) infusion on bone mineral density (BMD) in acute traumatic spinal cord injury (TSCI) patients compared to chronic TSCI patients. The findi...

KEY FINDING: Acute TSCI patients had higher bone turnover markers and sclerostin concentrations at baseline compared to chronic TSCI patients.

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Spinal Cord InjuryEndocrinologyResearch Methodology & Design

Short-Term and Long-Term Risk of Diabetes Mellitus among Patients with Spinal Cord Injury: A Nationwide Retrospective Cohort Study

Healthcare, 2024 • September 15, 2024

This study investigated the short-term and long-term risks of diabetes mellitus (DM) among patients with spinal cord injury (SCI) compared to a matched control group, considering the presence and seve...

KEY FINDING: The short-term risk of DM was significantly higher among patients with SCI compared to controls (OR 2.51, 95% CI 1.91–3.27).

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Spinal Cord InjuryEndocrinologyNeurology

Influence of Diabetes Mellitus on Neurological Recovery in Older Patients With Cervical Spinal Cord Injury Without Bone Injury: A Retrospective Multicenter Study

Global Spine Journal, 2024 • January 1, 2024

This study aimed to investigate the impact of diabetes on post-injury complications and neurological recovery, and the relationship between moderate-severe diabetes and neurological recovery in patien...

KEY FINDING: Diabetic patients with CSCI without bone injury achieved similar neurological function improvements compared to non-diabetic patients.

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Cardiovascular ScienceEndocrinologyNeurology

Spinal cord stimulation induces Neurotrophin‑3 to improve diabetic foot disease

Medical Molecular Morphology, 2025 • November 17, 2024

The study investigates the therapeutic effect of spinal cord stimulation (SCS) on diabetic foot disease using clinical assessments of patients and a rat model of diabetic foot injury. SCS therapy impr...

KEY FINDING: SCS therapy improved the condition of patients with diabetic ischemic foot disease, as indicated by clinical assessments.

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