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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Dermatology Research

Browse the latest research summaries in the field of dermatology for spinal cord injury patients and caregivers.

Showing 11-20 of 170 results

Spinal Cord InjuryDermatologyBiomechanics

Stiffening of the gluteal muscle increased the intramuscular stress: An in-silico implication of deep tissue injury

Heliyon, 2023 • February 3, 2023

This study investigates the relationship between gluteal muscle shear modulus and intramuscular stress/strain using a semi-3D finite element model of the human buttock to understand deep tissue injury...

KEY FINDING: Increased gluteal muscle stiffness, represented by a higher shear modulus, leads to increased compressive stress, strain energy density, and average von Mises stress within the muscle.

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OncologyDermatology

Marjolin’s ulcer in an ischial pressure sore presented with necrotizing soft tissue infection: A case report

Medicine, 2023 • March 15, 2023

This case report highlights the diagnostic challenges and treatment strategies for Marjolin's ulcer (MU) arising from a pressure sore, initially presenting as necrotizing soft tissue infection (NSTI)....

KEY FINDING: Marjolin's ulcer can mimic necrotizing soft tissue infection, making diagnosis challenging.

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Spinal Cord InjuryCritical CareDermatology

Predictors of hospital‑acquired pressure injuries in patients with complete spinal cord injury: a retrospective case–control study

BMC Musculoskeletal Disorders, 2023 • March 24, 2023

This retrospective case–control study examined the association between norepinephrine treatment and pressure injury (PI) formation in patients with acute complete spinal cord injury (SCI). The study f...

KEY FINDING: Male gender was associated with a significantly increased risk of developing pressure injuries (OR:34.1; ­CI95:2.3–506.5, p = 0.010).

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Spinal Cord InjuryGastroenterologyDermatology

Understanding the impact of spinal cord injury on the microbiota of healthy skin and pressure injuries

Scientific Reports, 2023 • August 16, 2023

The study investigates the microbiome composition of skin and pressure injuries (PI) in individuals with spinal cord injury (SCI). It aims to understand the differences in bacterial communities betwee...

KEY FINDING: Skin had lower microbial diversity compared to pressure injuries (PI).

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Critical CareBiomedicalDermatology

A pressure monitoring approach for pressure ulcer prevention

BMC Biomedical Engineering, 2023 • August 1, 2023

This study addresses the problem of pressure ulcers (PUs), which disproportionately affect individuals with impaired mobility, leading to tissue damage from prolonged pressure. Effective prevention st...

KEY FINDING: A tunable continuous pressure magnitude and duration monitoring approach is proposed that can account for the accumulated damaging effect of an applied pressure and pressure relief over a prolonged period.

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ImmunologyDermatology

Retrospective analysis of the management of pelvic decubitus ulcers and their outcomes

Therapeutic Advances in Infectious Disease, 2023 • August 7, 2023

This retrospective study analyzed outcomes of patients with decubitus ulcer-related osteomyelitis who were not candidates for myocutaneous flapping. The study compared outcomes between patients treate...

KEY FINDING: Patients with decubitus-related osteomyelitis who did not undergo myocutaneous flapping had high rates of hospital readmission.

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PharmacologyNutrition & DieteticsDermatology

Simultaneous Administration of Hyperbaric Oxygen Therapy and Antioxidant Supplementation with Filipendula ulmaria Extract in the Treatment of Thermal Skin Injuries Alters Nociceptive Signalling and Wound Healing

Medicina, 2023 • September 17, 2023

This study investigates the effects of hyperbaric oxygen therapy (HBO) and antioxidant supplementation with Filipendula ulmaria extract, individually and simultaneously, in treating thermal skin injur...

KEY FINDING: Simultaneous administration of hyperbaric oxygen therapy and antioxidant supplementation with Filipendula ulmaria extract significantly ameliorated the macroscopic and histopathological characteristics of the wound area and healing.

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PharmacologyPain ManagementDermatology

Metformin alleviates pathologic pain in mice with radiation dermatitis by inhibiting p38MAPK/NF-κB signaling pathway

J South Med Univ, 2023 • October 1, 2023

This study investigated the therapeutic effect of metformin on pathological pain in mice with radiation dermatitis and explored the underlying mechanism. The results showed that metformin can signific...

KEY FINDING: Metformin alleviated radiation dermatitis symptoms in mice compared to the model group and a positive control group (Gabapentin).

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HealthcareDermatology

WHS Guidelines for the Treatment of Pressure Ulcers – 2023 update

Wound Repair Regen, 2024 • January 1, 2024

The 2023 WHS guidelines provide updated recommendations for pressure ulcer treatment, incorporating new evidence and addressing palliative care. The overall goal of the Wound Healing Society Guideline...

KEY FINDING: Repositioning schedules and avoiding positioning patients on pressure ulcers are crucial for prevention. The exact turning interval is not known and is derived empirically.

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SurgeryDermatology

Flap Survival after Reconstructive Surgery for Pressure Ulcers: A Cohort Study

PRS Global Open, 2023 • December 14, 2023

This study examined the outcomes of 111 reconstructive flap operations for pressure ulcers, finding a 90% viability rate one month post-operation. Multivariable analysis identified higher BMI, congeni...

KEY FINDING: Higher body mass index is associated with increased risk of flap failure.

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