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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 21-30 of 339 results

Cardiovascular ScienceRegenerative MedicineNeurology

Stem Cell Therapies for Restorative Treatments of Central Nervous System Ischemia–Reperfusion Injury

Cellular and Molecular Neurobiology, 2023 • February 7, 2022

Ischemic damage to the central nervous system (CNS) is a catastrophic postoperative complication of aortic occlusion subsequent to cardiovascular surgery that can cause brain impairment and sometimes ...

KEY FINDING: Mesenchymal stem cells (MSCs) have the capacity for self-renewal and can differentiate into any type of cell and exhibit immunomodulatory, anti-inflammatory, and tissue repair properties.

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Cardiovascular ScienceOncologyNeurology

Extranodal classical Hodgkin lymphoma involving the spinal cord: case report and review of the literature

CNS Oncology, 2022 • June 13, 2022

This case report highlights the rare occurrence of extranodal Hodgkin lymphoma involving the spinal cord, emphasizing the importance of considering this possibility in patients presenting with spinal ...

KEY FINDING: The study presents two cases of extranodal Hodgkin lymphoma involving the spinal cord without contiguous bone involvement, a rare presentation of the disease.

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Cardiovascular ScienceOncologyNeurology

Epidural Spinal Cord Compression as the Presenting Manifestation of Acute Myeloid Leukemia: A Case Report and Literature Review

Internal Medicine, 2023 • January 1, 2023

This case report details a 14-year-old boy presenting with spinal cord compression as the initial manifestation of acute myeloid leukemia (AML). The compression was caused by an epidural mass, which w...

KEY FINDING: A rare presentation of AML in a 14-year-old boy was spinal cord compression due to an epidural mass.

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Spinal Cord InjuryCardiovascular SciencePulmonology

Effects of C2 hemisection on respiratory and cardiovascular functions in rats

Neural Regeneration Research, 2023 • February 1, 2023

The study investigates the impact of C2 spinal cord hemisection (C2HS) on respiratory, cardiovascular, and renal functions in rats, revealing that diaphragm activity and systolic function are affected...

KEY FINDING: Global ventilation parameters were not impacted 7 days post-C2 hemisection, suggesting compensation.

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Cardiovascular ScienceSurgery

The Effect of Supraceliac 1 versus Infraceliac Landing Zone on Outcomes following Fenestrated Endovascular Repair of Juxta-/Pararenal Aortic Aneurysms

J Vasc Surg, 2023 • January 1, 2023

This study assessed perioperative outcomes in patients who underwent juxta-/pararenal FEVAR with supraceliac versus infraceliac sealing in the Vascular Quality Initiative (VQI). Compared with sealing ...

KEY FINDING: Supraceliac sealing was associated with a lower risk of type-IA completion endoleaks compared with infraceliac sealing.

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Cardiovascular ScienceNeurologyGenetics

Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect

J Clin Invest, 2022 • November 1, 2022

This study identifies microvascular defects in SMA patients, transgenic SMA mice, and cellular models with SMN deficiency. It reveals a widespread microvascular pathology that is amenable to systemica...

KEY FINDING: SMA patients exhibit retinal vascular defects, characterized by a less dense and less complex primary retinal vasculature compared to age-matched controls.

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Cardiovascular ScienceAlternative MedicinePharmacology

Puerarin: A protective drug against ischemia-reperfusion injury

Frontiers in Pharmacology, 2022 • August 24, 2022

Puerarin demonstrates a protective effect against ischemia-reperfusion injury (IRI) in various organs, including the heart, brain, spinal cord, lung, and intestine. The protective mechanisms of puerar...

KEY FINDING: Puerarin reduces myocardial apoptosis by reducing lactic acid production, inhibiting inflammatory response, inhibiting oxidative stress, opening the potassium channel and activating protein kinase C (PKC), promoting myocardial angiogenesis and inhibiting autophagy.

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Cardiovascular ScienceSurgery

Descending thoracic aortic repair outcomes for chronic aortic dissection: a single-centre experience

Interact CardioVasc Thorac Surg, 2022 • September 14, 2022

This study evaluated the outcomes of descending thoracic aortic repair (DTAR) for chronic aortic dissection (CAD) at a single center, finding good early and long-term results. The study identified age...

KEY FINDING: Descending thoracic aortic repair for chronic aortic dissection resulted in good early and long-term results.

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Spinal Cord InjuryCardiovascular ScienceSurgery

Impact of Reconstructing Intercostal Artery on Spinal Cord Circulation During Open Surgery for Thoracoabdominal Aortic Aneurysm

Brazilian Journal of Cardiovascular Surgery, 2023 • January 1, 2023

This retrospective study evaluated the impact of selective intercostal artery reconstruction on spinal cord injury (SCI) during open thoracoabdominal aortic aneurysm (TAAA) repair. The study found a 4...

KEY FINDING: Paraplegia occurred in 4.7% of patients, and the hospital death rate was 5.9%.

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Cardiovascular ScienceSurgery

Bovine pericardial patch repair for abdominal aortic pseudoaneurysm to preserve lumbar arteries

Interact CardioVasc Thorac Surg, 2022 • October 31, 2022

This case report describes a successful aortic repair using bovine pericardium in a patient with a dissecting abdominal aorta pseudoaneurysm. The key objective was to preserve the lumbar arteries to m...

KEY FINDING: Aortic repair using a bovine pericardial patch was successfully performed to treat a pseudoaneurysm while preserving lumbar arteries.

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