Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Cardiovascular Science
  4. The Effect of Supraceliac 1 versus Infraceliac Landing Zone on Outcomes following Fenestrated Endovascular Repair of Juxta-/Pararenal Aortic Aneurysms

The Effect of Supraceliac 1 versus Infraceliac Landing Zone on Outcomes following Fenestrated Endovascular Repair of Juxta-/Pararenal Aortic Aneurysms

J Vasc Surg, 2023 · DOI: 10.1016/j.jvs.2022.08.007 · Published: January 1, 2023

Cardiovascular ScienceSurgery

Simple Explanation

This study compares outcomes of FEVAR for juxta-/pararenal aortic aneurysms based on the location of the proximal seal: supraceliac (above the celiac artery) versus infraceliac (below the celiac artery). The study found that supraceliac sealing was associated with a lower risk of type-IA endoleaks but a higher risk of certain complications. The researchers concluded that while supraceliac sealing might offer some benefits, clinicians need to be aware of the increased risk of perioperative morbidity.

Study Duration
2014-2021
Participants
1,486 patients who underwent FEVAR for juxta-/pararenal aneurysms
Evidence Level
Not specified

Key Findings

  • 1
    Supraceliac sealing was associated with a lower risk of type-IA completion endoleaks compared with infraceliac sealing.
  • 2
    There was no significant difference in perioperative or 3-year mortality between supraceliac and infraceliac sealing.
  • 3
    Supraceliac sealing was associated with higher odds of leg ischemia, acute kidney injury, and cardiac complications.

Research Summary

This study assessed perioperative outcomes in patients who underwent juxta-/pararenal FEVAR with supraceliac versus infraceliac sealing in the Vascular Quality Initiative (VQI). Compared with sealing at an infraceliac level, supraceliac sealing was associated with lower risk of type-IA endoleaks and similar mortality. Clinicians should be aware that supraceliac sealing may be associated with higher perioperative morbidity. Future studies with longer follow-up are needed.

Practical Implications

Careful Patient Selection

Clinicians should carefully evaluate patients undergoing FEVAR for juxta-/pararenal aneurysms to determine the optimal proximal sealing zone, considering the potential risks and benefits of supraceliac versus infraceliac sealing.

Meticulous Technique

Given the increased risk of complications associated with supraceliac sealing, meticulous surgical technique and postoperative monitoring are crucial to minimize perioperative morbidity.

Further Research Needed

Longer-term studies are needed to evaluate the durability of FEVAR with different proximal sealing zones and to comprehensively assess the risks and benefits of utilizing a higher sealing zone within the visceral aorta.

Study Limitations

  • 1
    Retrospective study design
  • 2
    Lack of long-term complications and reinterventions data in VQI
  • 3
    Collinearity between commercial FEVAR approvals and repair type (PMEG)

Your Feedback

Was this summary helpful?

Back to Cardiovascular Science