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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 261-270 of 339 results

Spinal Cord InjuryCardiovascular ScienceResearch Methodology & Design

Identification and Management of Cardiometabolic Risk after Spinal Cord Injury: Clinical Practice Guideline for Health Care Providers

Top Spinal Cord Inj Rehabil, 2018 • January 1, 2018

The guideline aims to improve care for patients with SCI by providing recommendations for clinicians and policymakers based on available evidence and expert consensus. It focuses on identifying and ma...

KEY FINDING: People with SCI have the same or greater risk for CMD as the non-disabled population.

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Spinal Cord InjuryUrologyCardiovascular Science

A randomized double-blind, placebo-controlled, cross-over trial assessing the effect of tadalafil (Cialis) on the cardiovascular response in men with complete spinal cord injury above the sixth thoracic level: A Pilot Study

Spinal Cord Series and Cases, 2018 • November 1, 2018

This study evaluated the effects of tadalafil on cardiovascular responses in men with spinal cord injuries above T6. The results indicated that tadalafil did not cause hypotension but led to a compens...

KEY FINDING: Systolic blood pressure did not change significantly in either the tadalafil or placebo group.

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Cardiovascular ScienceNeurorehabilitationRehabilitation

Guideline Approaches for Cardioendocrine Disease Surveillance and Treatment Following Spinal Cord Injury

Current Physical Medicine and Rehabilitation Reports, 2018 • November 15, 2018

Persons with spinal cord injuries (SCI) commonly experience individual risks and coalesced health hazards of the cardiometabolic syndrome (CMS). Evidence supports a therapeutic role for physical activ...

KEY FINDING: The CMS hazards of overweight/obesity, insulin resistance, hypertension, and dyslipidemia are strongly associated with physical deconditioning and are common after SCI.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

Effects of exercise interventions on cardiovascular health in individuals with chronic, motor complete spinal cord injury: protocol for a randomised controlled trial [Cardiovascular Health/Outcomes: Improvements Created by Exercise and education in SCI (CHOICES) Study]

BMJ Open, 2019 • January 1, 2019

This is a multicentre, randomised, controlled, clinical trial to compare the efficacy of arm cycle ergometry training (ACET) and body weight-supported treadmill training (BWSTT) on reducing arterial s...

KEY FINDING: The primary outcome measure will be change in arterial stiffness (cfPWV) from baseline.

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Cardiovascular SciencePhysiologyNeuroplasticity

Circulatory control of phrenic motor plasticity

Respir Physiol Neurobiol, 2019 • July 1, 2019

This review discusses how local circulatory control and oxygen delivery in the spinal cord regulate different pathways to phrenic motor plasticity. Acute intermittent hypoxia (AIH) elicits distinct me...

KEY FINDING: Moderate AIH induces serotonin-dependent pLTF, which is independent of tissue hypoxia and relies on carotid body chemoreceptor activation.

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Cardiovascular ScienceNeurologyTrauma

Spontaneous spinal subdural haematoma in a patient on apixaban

BMJ Case Rep, 2019 • January 1, 2019

A 68-year-old man on apixaban presented to the emergency department with back pain following a long-haul flight. Investigations for pulmonary embolus and aortic dissection were negative and he was dis...

KEY FINDING: The patient's spinal subdural haematoma was initially missed, leading to multiple presentations and worsening symptoms.

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Cardiovascular ScienceNeuroimagingNeurology

Functional Ultrasound Imaging of Spinal Cord Hemodynamic Responses to Epidural Electrical Stimulation: A Feasibility Study

Frontiers in Neurology, 2019 • March 26, 2019

This study demonstrates the feasibility of using functional ultrasound (fUS) imaging to monitor spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in animal models. The researc...

KEY FINDING: fUS can detect spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in both rat and swine models.

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Spinal Cord InjuryCardiovascular ScienceNeurology

The Blood Pressure Pendulum following Spinal Cord Injury: Implications for Vascular Cognitive Impairment

International Journal of Molecular Sciences, 2019 • May 18, 2019

This review examines the impact of extreme blood pressure lability on vascular cognitive impairment (VCI) in individuals with spinal cord injury (SCI). It highlights the potential mechanisms by which ...

KEY FINDING: Individuals with SCI experience significant cardiovascular impairments, including drastic blood pressure fluctuations, which can lead to vascular cognitive impairment.

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Spinal Cord InjuryCardiovascular SciencePharmacology

Case report – Gluteal hematoma in two spinal cord patients on enoxaparin for venous thromboembolism prophylaxis: evidence needed for a wiser choice

Spinal Cord Series and Cases, 2019 • March 19, 2019

The case report highlights the occurrence of gluteal hematomas in two patients with chronic spinal cord injury who were receiving prophylactic enoxaparin for venous thromboembolism (VTE). The authors ...

KEY FINDING: Two patients with chronic SCI developed gluteal hematomas while on prophylactic enoxaparin, requiring surgical intervention and delaying rehabilitation.

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Cardiovascular ScienceNeurorehabilitationRehabilitation

Effects of High-Intensity Interval Training Versus Moderate-Intensity Training on Cardiometabolic Health Markers in Individuals With Spinal Cord Injury: A Pilot Study

Top Spinal Cord Inj Rehabil, 2019 • May 16, 2019

This pilot study compared the effects of 6 weeks of low-volume HIIT versus MIT using arm crank ergometer exercise to improve cardiometabolic health markers in individuals with longstanding SCI. The pr...

KEY FINDING: Both HIIT and MIT improved insulin sensitivity, cardiovascular fitness, and muscular strength in individuals with SCI.

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