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  4. Spontaneous spinal subdural haematoma in a patient on apixaban

Spontaneous spinal subdural haematoma in a patient on apixaban

BMJ Case Rep, 2019 · DOI: 10.1136/bcr-2018-227311 · Published: January 1, 2019

Cardiovascular ScienceNeurologyTrauma

Simple Explanation

A 68-year-old man on apixaban presented to the emergency department with back pain following a long-haul flight. He was initially discharged with analgesia for mechanical back pain, but presented three more times with worsening symptoms. Further investigation revealed a spinal subdural haematoma, which was managed conservatively. He was discharged for rehabilitation with good neurological recovery. This case highlights the importance of considering iatrogenic haemorrhage in anticoagulated patients presenting with pain and neurological symptoms, and the potential for conservative management in certain cases of spontaneous spinal subdural haematoma.

Study Duration
Not specified
Participants
One 68-year-old man
Evidence Level
Case Report

Key Findings

  • 1
    The patient's spinal subdural haematoma was initially missed, leading to multiple presentations and worsening symptoms.
  • 2
    Conservative management, rather than surgical intervention, led to a good neurological recovery in this case.
  • 3
    The case highlights the potential for delayed diagnosis of spontaneous spinal subdural haematoma in patients on apixaban.

Research Summary

A 68-year-old man on apixaban presented to the emergency department with back pain following a long-haul flight. Investigations for pulmonary embolus and aortic dissection were negative and he was discharged with analgesia for mechanical back pain. He presented three more times with worsening back pain, third time with urinary retention and the fourth time with lower limb weakness and loss of coordination. He was found to have a spinal subdural haematoma on MRI and transferred to a tertiary centre He was managed conservatively and discharged for rehabilitation with good neurological recovery.

Practical Implications

Clinical Vigilance

Maintain a high index of suspicion for spontaneous spinal subdural haematoma in patients on anticoagulants presenting with back pain or neurological symptoms.

Conservative Management

Consider conservative management as a viable option for SSDH, especially in patients with mild neurological deficits.

Reversal Agents

Be aware of the availability and potential use of reversal agents like andexanet alfa in managing SSDH in patients on NOACs.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Conservative management outcome may not be applicable to all cases of SSDH.
  • 3
    Delay in diagnosis could have influenced the patient's outcome.

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