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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 251-260 of 339 results

Spinal Cord InjuryCardiovascular ScienceNeurology

Using the autonomic standards to assess orthostatic hypotension in persons with SCI: a case series

Spinal Cord Series and Cases, 2017 • October 10, 2017

Impaired blood pressure control in SCI patients can result from medical issues and autonomic dysfunction. Management strategies for orthostatic hypotension vary based on the stage of SCI, its root cau...

KEY FINDING: Case 1 showed antidepressants for neuropathic pain can adversely influence orthostatic hypotension.

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Spinal Cord InjuryCardiovascular Science

Assessing Heart Rate Variability As a Surrogate Measure of Cardiac Autonomic Function in Chronic Traumatic Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2015 • January 1, 2015

This study aimed to determine if there are differences in heart rate variability (HRV) measures across neurological level of impairment (NLI) and American Spinal Cord Injury Association Impairment Sca...

KEY FINDING: No significant differences in HRV measures were found across neurological level of impairment (NLI) and American Spinal Cord Injury Association Impairment Scale (AIS) subgroups.

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Spinal Cord InjuryCardiovascular SciencePediatrics

Use of ambulatory blood pressure monitoring in adolescents with SCI: a case series

Spinal Cord Series and Cases, 2017 • November 3, 2017

This case series presents the cardiovascular profile of three adolescent patients with chronic SCI, ages 14–16, following 2 or 3 days of 24-h Ambulatory Blood Pressure Monitoring (ABPM). The ABPM findin...

KEY FINDING: The ABPM findings indicate significant variation in 24-h cardiovascular hemodynamics among adolescents with SCI.

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Spinal Cord InjuryCardiovascular ScienceEndocrinology

Sex dimorphism in the distribution of adipose tissue and its influence on proinflammatory adipokines and cardiometabolic profiles in motor complete spinal cord injury

The Journal of Spinal Cord Medicine, 2019 • July 1, 2019

This study investigated the influence of sex on adipose tissue distribution and its relationship with inflammatory adipokines and cardiometabolic profiles in individuals with motor complete spinal cor...

KEY FINDING: Male participants with SCI had significantly greater visceral adipose tissue (VAT) volume and VAT:SAT ratio compared to females.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

Risk of venous thromboembolism during rehabilitation of patients with spinal cord injury

PLoS ONE, 2018 • March 28, 2018

This study evaluated the risk of venous thromboembolism (VTE) and bleeding events in spinal cord injury (SCI) patients during rehabilitation. The study found that SCI patients are at risk of VTE and b...

KEY FINDING: The probability of developing VTE after 6 months of rehabilitation was 2% (95% CI 0–4.4%) after excluding patients with VTE detected within 2 days of admission.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

Passive Limb Movement Intervals Results in Repeated Hyperemic Responses in Those with Paraplegia

Spinal Cord, 2018 • October 1, 2018

The study investigated the effects of repeated passive limb movement (PLM) on blood flow in individuals with paraplegia. Nine participants with complete spinal cord injuries underwent five one-minute ...

KEY FINDING: Repeated one-minute bouts of PLM resulted in consistent and significant increases in femoral artery blood flow (FABF) during each bout.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat

Journal of Visualized Experiments, 2018 • May 30, 2018

This study demonstrates the use of laser Doppler flowmetry (LDF) techniques, including both imaging and monitoring, to analyze spinal cord microcirculation in a rat model of spinal cord injury (SCI). ...

KEY FINDING: Spinal cord injury (SCI) induced a reduction of blood flow (BF), with the epicenter of the injury showing lower BF compared to rostral and caudal regions.

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Spinal Cord InjuryCardiovascular ScienceGenetics

MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis

Ann Diagn Pathol, 2018 • October 1, 2018

This study investigates the role of miR-155 in spinal cord paralysis following aortic cross-clamping (ACC) in mice. The findings indicate that miR-155 contributes to gray matter edema and paralysis by...

KEY FINDING: Increased miR-155 expression in neurons and endothelial cells of the spinal cord is associated with paralysis in a mouse model of aortic cross-clamping (ACC).

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Spinal Cord InjuryCardiovascular ScienceGenetics

Establishing a threshold to predict risk of cardiovascular disease from the serum triglyceride and high-density lipoprotein concentrations in persons with spinal cord injury

Spinal Cord, 2018 • November 1, 2018

This report explores the relationship between circulating TG and HDL-C concentrations, and more specifically, the serum TG concentrations at which serum HDL-C equals 40 mg/dl in SCI cohorts that are a...

KEY FINDING: The serum TG concentration that intersects with a serum HDL-C of 40 mg/dl is lower in persons with SCI than in the general population.

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Cardiovascular ScienceNeurologyRehabilitation

Spinal cord infarction during physical exertion due to polycythemia vera and aortoiliac occlusive disease: A case report

Medicine, 2018 • August 31, 2018

This case report details a 56-year-old man who developed spinal cord infarction due to polycythemia vera and aortoiliac occlusive disease after heavy physical exertion. The patient presented with acut...

KEY FINDING: Spinal cord infarction can be caused by polycythemia vera (PV) in conjunction with aortoiliac occlusive disease, leading to aortic thrombosis.

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