Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,881-3,890 of 12,052 results
Frontiers in Immunology, 2022 • October 13, 2022
This study investigates the role of IRG1/itaconate in neuropathic pain, demonstrating that endogenous itaconate levels increase in the spinal cord following nerve injury. Deficiency of IRG1 exacerbate...
KEY FINDING: The levels of itaconate and IRG1 in the spinal cord significantly increased after CCI (chronic constriction nerve injury).
Spinal Cord, 2023 • October 13, 2022
This study aimed to identify the psychosocial barriers and facilitators impacting sexual function and satisfaction post-SCI from the perspective of people living with the injury. Six themes emerged: I...
KEY FINDING: Participants face barriers due to societal stereotypes and stigmatization, impacting their sexual confidence and self-esteem.
Medicina, 2022 • October 13, 2022
Robotic-assisted gait training (RAGT) allows SCI patients to perform effective, prolonged locomotor training without specific side effects, increasing mobility, improving walking, and reducing spastic...
KEY FINDING: Robotic devices, combined with virtual reality, increase patient motivation and improve walking and balance via neuroplasticity.
Biomedicines, 2022 • October 13, 2022
The article reviews current interventions for spinal cord injury (SCI) treatment, focusing on rehabilitation phases and emphasizing a neuroplasticity-based multimodal approach. It highlights the integ...
KEY FINDING: Biomolecular approaches alone have modest outcomes in SCI treatment.
Frontiers in Rehabilitation Sciences, 2022 • October 13, 2022
This study evaluated the combined effects of robotic exoskeleton and functional electrical stimulation (FES) training on muscle composition during over-ground gait training in persons with acute spina...
KEY FINDING: Significant improvements were observed in muscle volume in the exoskeleton intervention group when compared to only standard-of-care.
Cureus, 2022 • October 13, 2022
Autonomic dysreflexia (AD) is a life-threatening condition that affects patients with spinal cord injuries (SCI) at the T6 level and above, triggered by noxious stimuli below the neurological level of...
KEY FINDING: The case report highlights that autonomic dysreflexia (AD) can be easily missed by medical staff unfamiliar with the condition, leading to delayed diagnosis and treatment.
Spinal Cord Series and Cases, 2022 • October 12, 2022
This pilot study assessed the adherence to and impact of a home-based high-intensity inspiratory muscle training (IMT) program on individuals with spinal cord injury (SCI). The study found that partic...
KEY FINDING: Participants completed an average of 69% of their training days in the first month of daily IMT, and 65% overall.
Neurobiology of Pain, 2022 • October 12, 2022
This study investigates sex-specific differences in spinal cord microglial activation and myeloid cell infiltration following peripheral injury using a mouse model of complex regional pain syndrome (C...
KEY FINDING: Spinal cord microglial activation is attenuated and delayed in females compared to males after peripheral injury.
BMJ Open, 2022 • October 12, 2022
This study aims to evaluate the Caring Connections intervention, a peer-based letter writing program, for reducing loneliness and perceived social isolation in individuals with SCI/D through a randomi...
KEY FINDING: The study hypothesizes that the Caring Connections intervention will lead to a reduction in loneliness among participants compared to the control group after the 6-month intervention period.
International Journal of Spine Surgery, 2022 • October 12, 2022
This systematic review summarizes the existing literature regarding the use of amniotic membrane preparations, treatment regimens, and indications within spinal surgery. The review of reported studies...
KEY FINDING: Amnion products show promising effects in reducing epidural adhesions and scar tissue after spine surgery.