Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Latest Research

Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 3,871-3,880 of 12,052 results

PharmacologyNeurologyTrauma

Transverse Myelitis in Naloxone Reversible Acute Respiratory Failure—A Case Report

JETem, 2022 • October 15, 2022

Transverse myelitis (TM) is a rare inflammatory myelopathy presenting as bilateral neurologic deficit localized to the spinal cord. Described in this case report is TM presenting after a respiratory a...

KEY FINDING: MRI revealed increased signal throughout the spinal cord from C-1 to the conus medullaris with mild expansion consistent with transverse myelitis.

Read Summary
SurgeryOrthopedicsBiomechanics

Finite element analysis of the indirect reduction of posterior pedicle screw fixation for a thoracolumbar burst fracture

Medicine, 2022 • October 14, 2022

The study uses finite element analysis to simulate indirect reduction of thoracolumbar burst fractures with posterior pedicle screw fixation, focusing on the mechanics of vertebral body restoration an...

KEY FINDING: Extension (positional reduction) helps restore the normal height and kyphosis of the injured vertebrae, concentrating stress on the upper disc.

Read Summary
ImmunologyOrthopedicsBiomedical

Mechanical strength of antibiotic‑loaded PMMA spacers in two‑stage revision surgery

BMC Musculoskeletal Disorders, 2022 • October 14, 2022

This study evaluates the mechanical strength of six different dual antibiotic-loaded bone cement (dALBC) preparations made from three commonly used PMMA bone cements (Copal spacem, Copal G + V, Palaco...

KEY FINDING: Copal G + V showed the highest bending strength after 24 hours, but after six weeks, the bending strength decreased in all preparations.

Read Summary
SurgerySpinal DisordersRehabilitation

Aggressive Vertebral Hemangioma and Spinal Cord Compression: A Particular Direct Access Case of Low Back Pain to Be Managed—A Case Report

Int. J. Environ. Res. Public Health, 2022 • October 14, 2022

This case report highlights the importance of red flags screening in a direct access environment and describes the clinical reasoning that led a physical therapist (PT) to refer a patient with low bac...

KEY FINDING: Red flags screening is crucial, especially in direct access settings, for identifying underlying extra-professional pathologies in patients presenting with low back pain.

Read Summary
NeurologyRehabilitation

Linking Prioritized Occupational Performance in Patients Undergoing Spasticity-Correcting Upper Limb Surgery to the International Classification of Functioning, Disability, and Health

Occupational Therapy International, 2022 • October 14, 2022

This retrospective study mapped the prioritized occupational performance goals (POPG) of 60 patients undergoing upper limb spasticity-correcting surgery to the International Classification of Function...

KEY FINDING: Patients identified a wide range of occupational tasks they considered important to regain, with self-care activities being the most frequently targeted ICF domain.

Read Summary
Spinal Cord InjuryAssistive TechnologyRehabilitation

Feasibility of home hand rehabilitation using musicglove after chronic spinal cord injury

Spinal Cord Series and Cases, 2022 • October 14, 2022

This study examined the feasibility of using the MusicGlove device for hand rehabilitation in individuals with chronic spinal cord injury (SCI). The results indicated that MusicGlove is a feasible opt...

KEY FINDING: Participants with SCI demonstrated higher levels of compliance and completed more gripping movements compared to participants in previous stroke studies using the same MusicGlove device.

Read Summary
Spinal Cord InjuryRegenerative MedicineNeurology

Transplanting neurofibromatosis-1 gene knockout neural stem cells improve functional recovery in rats with spinal cord injury by enhancing the mTORC2 pathway

Experimental & Molecular Medicine, 2022 • October 14, 2022

The study demonstrates that knocking out NF-1 in NSCs improves their survival and neuronal differentiation both in vitro and in vivo. Transplanting these modified NSCs into rats with SCI promotes tiss...

KEY FINDING: Knocking out NF-1 in NSCs enhances their anti-apoptotic ability in vitro, protecting them from cell death.

Read Summary
Regenerative MedicineOrthopedicsBioinformatics

Single-cell transcriptomics reveals variable trajectories of CSPCs in the progression of osteoarthritis

Heliyon, 2022 • October 13, 2022

This study investigates the dynamics of cartilage-derived stem/progenitor cells (CSPCs) in osteoarthritis (OA) progression using single-cell transcriptomic data. The research reveals that CSPC heterog...

KEY FINDING: CSPCs exhibit significant heterogeneity that is closely associated with the progression of OA, indicating that the characteristics of CSPCs change during OA progression.

Read Summary
SurgeryBiomedical

Cervical subtotal discectomy prosthesis validated in non-human primate model: A novel artificial cervical disc replacement concept?

Frontiers in Bioengineering and Biotechnology, 2022 • October 13, 2022

The study evaluated a novel cervical subtotal discectomy prosthesis (CSDP) in a non-human primate model, focusing on its safety, osseointegration, and biomechanical stability. The CSDP demonstrated ex...

KEY FINDING: The CSDP constituent titanium alloy (Ti6Al4V-AO) showed extended adhesion, remarkable viability status, and cell proliferation when co-cultured with mouse embryo osteoblast precursor cells.

Read Summary
PharmacologyGeneticsMusculoskeletal Medicine

The Therapeutic and Prognostic Role of Clusterin in Diverse Musculoskeletal Diseases: A Mini Review

Physiol. Res., 2022 • October 13, 2022

This mini-review aims to introduce the association between Secretory clusterin/apolipoprotein J (sCLU) and diverse musculoskeletal diseases. Recent findings of sCLU in these musculoskeletal diseases p...

KEY FINDING: sCLU is associated with inflammatory responses, tissue degeneration, and cellular apoptosis during acute and subacute traumatic SCI.

Read Summary
Previous
1...387388389...1206
Next