Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 301-310 of 12,052 results
World J Mens Health, 2025 • January 1, 2025
This review summarizes the role of autophagy in erectile dysfunction (ED), focusing on how it affects endothelial cells, smooth muscle cells, penile fibrosis, and nerve injury. It highlights the poten...
KEY FINDING: Autophagy plays a significant role in maintaining the homeostasis of corpus cavernosum endothelial cells (CCECs) and determining their survival and death, influencing ED, particularly in diabetes mellitus-induced ED (DMED).
Anim Models Exp Med, 2025 • January 1, 2025
The study established a rat model of spinal cord compression and decompression to investigate SCII following decompressive cervical laminectomy. The model showed that spinal cord decompression leads t...
KEY FINDING: Spinal cord compression led to abnormal mechanical pain and decreased forepaw grip strength in rats.
World Neurosurgery: X, 2025 • January 1, 2025
This study evaluated the impact of Chetomin on histopathological features in a rat model of acute spinal cord injury, comparing its effects to methylprednisolone. The findings suggest that Chetomin ha...
KEY FINDING: Chetomin administration 8h post-injury decreased IL-6 and VEGF expression.
Eur J Neurol, 2025 • January 1, 2025
This systematic review traces the evolution of Queckenstedt's test, a routine diagnostic procedure for CSF space constriction. Clinical studies investigated its diagnostic accuracy against operative f...
KEY FINDING: Queckenstedt's test was widely adopted globally for diagnosing spinal canal obstruction, particularly spinal tumors.
Orthopaedic Surgery, 2025 • January 1, 2025
The study introduces and evaluates the C1ZAS technique with an “in-out-in” approach as an alternative to C1 PS placement for AAD patients, especially those with narrow C1 pedicles. The radiographic an...
KEY FINDING: The C1ZAS technique, using an “in-out-in” approach, is a feasible alternative to C1 pedicle screw (PS) placement, particularly in patients with AAD and narrow C1 pedicles.
Orthopaedic Surgery, 2025 • January 1, 2025
This study aimed to investigate the clinical outcomes of ACAF for cervical stenosis patients with CCS due to hyperextension injury. Finally, 13 patients (7 male and 6 female) with the minimum of 12-m...
KEY FINDING: ACAF can be a good option for treating CCS patients due to hyperextension injury with underlying cervical spondylosis and stenosis.
Eur J Neurol, 2025 • January 1, 2025
CHEPs revealed distinct patterns of spinal cord impairment independent of structural T2-positive lesions, which were associated with measures of cord motion. CHEPs thus provide valuable complementary...
KEY FINDING: Abnormal CHEPs were present in T2-positive DCM (C6:41%; C8:32%; T4:24%) and T2-negative DCM (C6:35%; C8:54%; T4:26%).
BMC Musculoskeletal Disorders, 2025 • January 1, 2025
This study assessed the efficacy of posterior trans-intervertebral osteotomy with anterior support (TIOAS) in patients with ankylosing spondylitis using computer simulations for preoperative planning....
KEY FINDING: Patients who underwent posterior trans-intervertebral osteotomy with anterior support achieved good clinical results with favorable correction rates and minimal estimated blood loss.
Neurosurgical Review, 2025 • January 1, 2025
This study compares the surgical outcomes of DREZL between patients with SCI and those with CEI to investigate predictors of favorable operative outcomes. The CEI group demonstrated significant pain i...
KEY FINDING: Patients with CEI had significantly better long-term pain reduction after DREZotomy compared to those with SCI.
CNS Neuroscience & Therapeutics, 2025 • January 1, 2025
The study aimed to understand how NDSM, known for analgesic efficacy, works to relieve pain, focusing on GABAA receptors and neuroinflammation. The results indicate that NDSM's analgesic effects are p...
KEY FINDING: NDSM demonstrates significant analgesic effects against chronic pain in both pain-evoked and pain-suppressed behavioral assays.