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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 131-140 of 12,052 results

Spinal Cord InjuryUrologyNeurology

Early Sacral Neuromodulation: A Promising Opportunity or an Overload for Patients with a Recent Spinal Cord Injury? A Cross-Sectional Study

J. Clin. Med., 2025 • February 6, 2025

The study investigated patients’ attitudes toward early sacral neuromodulation (SNM) for neurogenic lower urinary tract dysfunction (nLUTD) after spinal cord injury (SCI). Results showed that a signif...

KEY FINDING: 61.9% of patients stated they would have consented to early therapy prior to the emergence of their neurogenic lower urinary tract dysfunction.

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Spinal Cord InjuryRegenerative MedicineNeurology

Conditioned medium derived from mesenchymal stem cells and spinal cord injury: A review of the current therapeutic capacities

IBRO Neuroscience Reports, 2025 • February 6, 2025

Spinal cord injury (SCI) presents significant challenges due to its high incidence and difficult treatment. Mesenchymal stem cells (MSCs) offer a promising approach for treating neurological problems....

KEY FINDING: MSC-derived CM contains growth factors and cytokines that protect nerve cells. These include stem cell factor (SCF), vascular endothelial growth factor (VEGF), and glial cell line-derived neurotrophic factor (GDNF).

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Spinal Cord InjuryPharmacologyMedical Imaging

Validation of qMT and CEST MRI as Biomarkers of Response to Treatment After Lumbar Spinal Cord Injury in Rats

NMR in Biomedicine, 2025 • February 6, 2025

This study validated multiparametric chemical exchange saturation transfer (CEST) and quantitative magnetization transfer (qMT) magnetic resonance imaging (MRI) biomarkers for assessing SCI severity, ...

KEY FINDING: qMT PSR measurements reflect the myelination status of the white matter tissue. The riluzole treatment group indicated significantly higher PSR values in white matter voxels at the epicenter of injury compared to the HBC vehicle treatment group.

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Spinal Cord InjuryAssistive TechnologyRehabilitation

Effects of Gait Rehabilitation Robot Combined with Electrical Stimulation on Spinal Cord Injury Patients’ Blood Pressure

Sensors, 2025 • February 6, 2025

This study investigated the effects of a gait rehabilitation robot combined with functional electrical stimulation (FES) on orthostatic stress in intermediate-phase spinal cord injury (SCI) patients. ...

KEY FINDING: Earlobe blood flow (EBF) decreased in tilt table training (TT) but increased in robotic training (RT) at the 0.5-min slope (p = 0.03).

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Biomedical

A nanotwinned-alloy strategy enables fast sodium deposition dynamics

Nature Communications, 2025 • February 6, 2025

The study introduces a nanotwinned alloy strategy using high-pressure solid solution and Joule-heating treatment to improve sodium deposition dynamics in sodium metal batteries. The resulting nanotwin...

KEY FINDING: High-pressure solid solution extends Si solubility in Al, forming nanotwinned-Si particles through Joule-heating treatment.

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Spinal Cord InjuryNeurologyRehabilitation

Epidural Stimulation of the Lumbosacral Spinal Cord Improves Trunk Lean Distances in Individuals with Cervical Spinal Cord Injury

Biomedicines, 2025 • February 6, 2025

This study investigated the acute effects of trunk-specific spinal cord epidural stimulation (scES) on trunk control in individuals with chronic cervical spinal cord injury (SCI). The results indicate...

KEY FINDING: Trunk-specific scES led to increased trunk anterior–posterior displacement during forward/back lean activities.

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PharmacologyNeurologyRehabilitation

Spinal Cord Stimulation for Functional Restoration in Spinal Cord Injury: A Narrative Review

Cureus, 2025 • February 6, 2025

SCS has emerged as a groundbreaking therapeutic modality for promoting neurological recovery in SCI by targeting residual neural pathways and enhancing neuroplasticity, offering renewed hope for indiv...

KEY FINDING: SCS activates large-to-medium afferent fibers, enhancing the interneural connections between sensory afferents and motoneurons. This strengthens monosynaptic reflex activation onto motoneurons that control agonist muscles.

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NeurologySurgeryRehabilitation

Scientific Advances in Neural Regeneration After Spinal Cord Injury

Cureus, 2025 • February 6, 2025

Neural regeneration holds promise as a therapeutic approach for SCI, with cell-based therapies showing the most potential. Rehabilitation, often overlooked, is a vital noninvasive approach that enhanc...

KEY FINDING: Electrical stimulation of the spinal cord can restore impaired neurological functions when applied to the spinal segments containing the neurons responsible for these functions.

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Cardiovascular ScienceSurgery

Contemporary outcomes of open thoraco-abdominal aortic repair: a single-centre experience

Interdiscip CardioVasc Thorac Surg, 2025 • February 5, 2025

This study reports the outcomes of open thoraco-abdominal aortic aneurysm (TAAA) repair at a single academic medical center from 2015 to 2023, involving 190 patients. The primary endpoint was operativ...

KEY FINDING: Operative mortality was 7.9%, with similar rates in elective (7.5%) and non-elective (9.1%) cases.

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Surgery

Tracheal Reconstruction With a Clavicle-attached Sternocleidomastoid Muscle Flap Tolerant to Positive Pressure Ventilation

PRS Global Open, 2025 • February 5, 2025

This case report describes the successful treatment of a 29-year-old man with extensive tracheal wall tissue defects after tracheostomy. The patient presented with loss of spontaneous breathing due to...

KEY FINDING: A clavicle-attached pedicled sternocleidomastoid muscle (SCM) flap can be used to reconstruct the tracheal wall in patients with extensive tracheal cartilage defects.

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