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  4. Contemporary outcomes of open thoraco-abdominal aortic repair: a single-centre experience

Contemporary outcomes of open thoraco-abdominal aortic repair: a single-centre experience

Interdiscip CardioVasc Thorac Surg, 2025 · DOI: 10.1093/icvts/ivaf019 · Published: February 5, 2025

Cardiovascular ScienceSurgery

Simple Explanation

Thoraco-abdominal aortic aneurysms (TAAAs) are dangerous if untreated, leading to high mortality. While endovascular treatment is an option, it's not always suitable, especially for younger patients or those with collagen disorders. This study examines the outcomes of open surgical repair of TAAAs at a single medical center between 2015 and 2023. The study included patients undergoing open surgical repair for TAAAs (Crawford-Safi Types I–V) from 2015 to 2023. Data on patient characteristics, surgical details, and postoperative outcomes were collected and analyzed. The main goal was to assess operative mortality, with secondary goals including spinal cord injury, stroke, and the need for dialysis. The results showed that open TAAA surgery, when performed by a specialized team following strict protocols, can effectively manage this complex condition. The study reported low rates of mortality and severe complications, suggesting that open repair remains a valuable option.

Study Duration
9 years (2015-2023)
Participants
190 patients with thoraco-abdominal aortic aneurysm
Evidence Level
Not specified

Key Findings

  • 1
    Operative mortality was 7.9%, with similar rates in elective (7.5%) and non-elective (9.1%) cases.
  • 2
    Spinal cord injury occurred in 7.4% of patients, with persistent paraparesis in 2.1% and paraplegia in 1.6% at discharge.
  • 3
    Acute kidney injury occurred in 38.4% of patients, with 6.9% requiring dialysis and 3.7% continuing dialysis at discharge.

Research Summary

This study reports the outcomes of open thoraco-abdominal aortic aneurysm (TAAA) repair at a single academic medical center from 2015 to 2023, involving 190 patients. The primary endpoint was operative mortality, while secondary endpoints included spinal cord injury, stroke, tracheostomy, and need for dialysis. The results showed an operative mortality rate of 7.9%, with stroke occurring in 5.8% of patients, tracheostomy required in 3.7%, and spinal cord injury observed in 7.4%. Acute kidney injury occurred in 38.4% of patients, with 6.9% needing dialysis. The study concludes that open TAAA surgery, supported by a multidisciplinary team approach and strict perioperative protocols, remains an effective treatment option for this complex patient population, demonstrating low rates of mortality and severe complications.

Practical Implications

Continued Relevance of Open Repair

Open TAAA repair remains a valid option, especially in centers with expertise and multidisciplinary teams, even with the rise of endovascular techniques.

Importance of Centralized Care

Centralization of care is crucial to consolidate surgical expertise and resources, ensuring high standards of care for complex TAAA repairs.

Perioperative Protocols

Strict adherence to perioperative protocols, including distal aortic perfusion, reimplantation of critical arteries, blood pressure management, and cerebrospinal fluid drainage, is paramount in optimizing patient outcomes.

Study Limitations

  • 1
    Single-center experience may limit generalizability.
  • 2
    Retrospective cohort study design.
  • 3
    Missing data addressed through complete case analysis.

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