Latest Research Summaries

KEY FINDING: The study identified 101 differentially expressed genes (DEGs) associated with SCI and chronic pain. Further analysis led to the identification of 15 hub genes and 4 potential candidate genes.

KEY FINDING: Tissue engineering strategies can address the limitations of conventional SCI treatments by delivering drugs and cells with specific effects to the injury site.

KEY FINDING: Muscle strength increased in both the stimulated and non-stimulated hands of patients with incomplete SCI after high-PAS treatment.

KEY FINDING: A low dose of tamoxifen effectively ablates PDGFRβ+ cells of the CNS in mice without reducing survival or causing significant systemic side effects, such as weight loss.

KEY FINDING: Hydrogels can provide mechanical support to the spine, fill defects, and facilitate localized drug delivery, enhancing therapeutic effects while reducing adverse reactions.

KEY FINDING: Parthenogenetic stem cells can differentiate into various cell types, including neural stem cells, mesenchymal stem cells, and cardiomyocytes, suggesting their broad therapeutic potential for regenerative medicine.

KEY FINDING: ALDF effectively alleviates symptoms of lumbar disc herniation, with significant improvements in JOA, ODI, and NRS scores postoperatively.

KEY FINDING: TPTD significantly increased bone mineral density and other key bone indicators after SCI in rats, while ALN did not show significant improvement in these areas.

KEY FINDING: HAL gait training inhibited abnormal antagonistic muscle activation in the patient's lower extremities, particularly after the first training section.

KEY FINDING: PI3Kd treatment increased sprouting of axons across the midline above the C4 lesion and reduced the number and distance of retraction bulbs from the lesion border.