Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 121-130 of 12,052 results
Journal of Translational Medicine, 2025 • February 11, 2025
This study investigated the effects of fecal microbiota transplantation (FMT) on motor function recovery in a spinal cord injury (SCI) mouse model. The results demonstrated that FMT restored gut micro...
KEY FINDING: FMT significantly improved motor function recovery in SCI mice compared to those treated with antibiotics alone, as shown by BMS scoring, inclined plane test, and footprint analysis.
International Journal of Nanomedicine, 2025 • February 11, 2025
This review summarizes the current research status of the application of biomaterials to the SCI treatment, in recent years, to provide some comprehensive information and reference value for future ex...
KEY FINDING: Biomaterial scaffolds can be used for drug delivery, cell load, and tissue engineering to facilitate the repair of SCIs, while acting as a scaffold and microenvironment for tissue growth with reduced inflammatory responses.
Cellular and Molecular Neurobiology, 2025 • February 11, 2025
This study investigated the effects of electroacupuncture (EA) on spinal cord injury (SCI) in rats, focusing on the role of urocortin 2 (UCN2) and the cAMP-PKA signaling pathway. EA treatment improved...
KEY FINDING: EA treatment significantly improved behavioral scores and hind-limb locomotion in rats with SCI at 7, 14, and 28 days post-injury.
Stem Cells Translational Medicine, 2025 • February 11, 2025
The study investigates how different immunomodulatory strategies (genetic immunodeficiency vs. pharmacological immunosuppression) affect the survival, integration, and gene expression of transplanted ...
KEY FINDING: X-SCID rats exhibited significantly higher retention of transplanted NPCs compared to both Wistar and RNU rats, indicating that both T and B cells play crucial roles in the rejection of xenografted human NPCs.
PLoS ONE, 2025 • February 10, 2025
This article describes the development of priorities and actions to improve the state of research, policy, and practice related to accessible housing in Canada for persons with disability or with acce...
KEY FINDING: The expert panel identified three clusters of priorities: engaging with all levels of government to support accessible housing efforts.
PLOS ONE, 2025 • February 10, 2025
The study developed a toolkit to facilitate the implementation of FES cycling for individuals with a newly acquired spinal cord injury (SCI) in acute care inpatient hospital settings. Participatory ac...
KEY FINDING: Four main themes were identified: healthcare provider toolkit content and categories, healthcare provider toolkit end product, collaborations between groups and institutions, and infrastructure.
Journal of Orthopaedic Surgery and Research, 2025 • February 10, 2025
This study retrospectively analyzed 22 patients with severe post-tubercular kyphosis (PTK) who underwent modified posterior vertebral column resection (mPVCR). The results demonstrated significant imp...
KEY FINDING: The modified PVCR technique resulted in a significant improvement in kyphosis angle (KA) from 129.5° to 43.7° postoperatively.
Fluids and Barriers of the CNS, 2025 • February 10, 2025
This study investigates the role of ependymal cilia and AQP4 in syringomyelia using a rat model. The findings highlight the significance of cilia on ependymal cells and the evolving microenvironment p...
KEY FINDING: Ependymal cilia are significantly reduced in syringomyelia, with altered morphology, and cell junctions between ependymal cells are loose and broken.
Frontiers in Neurology, 2025 • February 7, 2025
This study employs bibliometric analysis to explore trends and emerging hotspots in research on the relationship between glial cells and neuropathic pain. Based on literature data from the Web of Scie...
KEY FINDING: China and the United States are the leading countries in research on glial cells and neuropathic pain, with the University of California system being the top institution.
Brain and Spine, 2025 • February 7, 2025
This review provides an overview of recent advances in cell transplantation therapy, focusing on patients involved in clinical research. Over the past decade, numerous clinical studies of SCI have bee...
KEY FINDING: Promising results have been reported for patients with subacute SCI, especially in studies involving MSCs, such as those conducted with Stemirac, although no universally recognized breakthroughs have been achieved.