Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 111-120 of 12,052 results
Journal of Orthopaedic Surgery and Research, 2025 • February 14, 2025
This retrospective study compared PECD and UBE for CSR treatment, finding both effective in improving VAS and NDI scores. The study included 70 patients, with 40 undergoing PECD and 30 undergoing UBE....
KEY FINDING: UBE group had shorter operative time compared to the PECD group (65.6 ± 17.6 vs. 85.1 ± 24.2 min, p < 0.001), but the former had longer incision length than the latter (2.4 ± 0.4 cm vs. 1.3 ± 0.4 cm, p < 0.001).
Journal of Neural Engineering, 2025 • February 14, 2025
This study investigates the potential of electromagnetic stimulation to restore axonal conductance in locally demyelinated axons using a computational model. Results indicate that microcoil stimulatio...
KEY FINDING: Subthreshold microcoil stimulation depolarized node membranes, enhancing activation and restoring axonal conductance in demyelinated regions.
Brain Sci., 2025 • February 14, 2025
Spinal cord injury (SCI) leads to secondary complications like gut dysbiosis (GD) and NLRP3 inflammasome activation, impacting mental health due to disrupted gut microbiome and inflammatory processes....
KEY FINDING: Gut dysbiosis (GD) and activation of the NLRP3 inflammasome are significant secondary complications after spinal cord injury (SCI), impacting mental health.
Frontiers in Pharmacology, 2025 • February 14, 2025
This study investigated the effects of Rosa canina oligosaccharide liposomal formulation (Oligo-L) on sensory-motor function, following SCI in rats. The findings indicated that Oligo-L treatment led t...
KEY FINDING: Oligo-L treatment significantly improved neuropathic pain and motor function performance in rats with SCI from the first week post-injury.
Front. Rehabil. Sci., 2025 • February 13, 2025
The editorial advocates for integrating rehabilitation with advanced cellular, pharmacological, and neuromodulation therapies to enhance functional recovery in neurological conditions. It stresses the...
KEY FINDING: Combining rehabilitation with stem cell-based therapies can improve upper extremity function in cervical SCI, especially when using neuromodulation to activate neural circuits below the injury level.
Front. Sports Act. Living, 2025 • February 12, 2025
The study compared a whole of day activity accumulation (WODAA) program to a traditional planned arm crank exercise (PACE) program for physical activity promotion in manual wheelchair users with spina...
KEY FINDING: The WODAA group had significantly more daily arm movement/propulsion activity (Steps) compared to the PACE group over the final month of the intervention.
Journal of Rehabilitation Medicine, 2025 • February 12, 2025
This paper introduces the “360° Model of Research”, a novel framework designed to prioritize functioning as a primary health indicator, particularly for individuals living with health conditions. The ...
KEY FINDING: The 360° Model emphasizes functioning as a key health indicator, combining biological health with lived experience.
Biomedicines, 2025 • February 12, 2025
This study investigates the effects of Ganoderic Acid DM (GA-DM), a natural extract from Ganoderma lucidum, on B-cell lymphoma. The research demonstrates that GA-DM exhibits anti-proliferative activit...
KEY FINDING: GA-DM induces apoptosis in human B-cell lymphoma cell lines DB and Toledo, and orchestrates autophagy and apoptosis in the murine B-cell lymphoma cell line A20.
Journal of Nanobiotechnology, 2025 • February 11, 2025
The intestinal microbiome plays an important role in SCI and regulating intestinal microbiome promotes SCI repair. Pectin-Zein-IPA NPs treatment improves motor function recovery, inhibits the activati...
KEY FINDING: Pec-Zein-IPA NPs treatment improves motor function recovery and activates AKT/Nrf-2 signaling pathway following SCI.
Journal of Translational Medicine, 2025 • February 11, 2025
This study investigates the role of Follistatin-like 1 (FSTL1) in nucleus pulposus-derived mesenchymal stem cell (NP-MSC) apoptosis and intervertebral disc degeneration (IVDD). The findings reveal tha...
KEY FINDING: FSTL1 expression is elevated in NP-MSCs from degenerated intervertebral discs in both humans and rats.