Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,961-11,970 of 12,052 results
Molecular Pain, 2006 • April 3, 2006
The study investigated the role of PKC in spinal cord in mediating chronic injury-induced pain and its relationship with glutamate receptors. Activation of PKC in the spinal cord produces mechanical h...
KEY FINDING: Intrathecal injection of PDBu (phorbol 12,13 dibutyrate) decreased the mechanical withdrawal threshold bilaterally in a dose-dependent manner, indicating increased sensitivity to pain.
J Neurophysiol, 2006 • April 1, 2006
This study examined the effects of long-term neuromuscular electrical stimulation (NMES) training on musculoskeletal health in individuals with acute spinal cord injury (SCI). The primary outcomes wer...
KEY FINDING: Long-term NMES training resulted in significant improvements in plantar flexor muscle properties, including increased peak torque (+24%), torque-time integral (+27%), fatigue index (+50%), and torque rise time (+45%).
The Journal of Neuroscience, 2006 • March 29, 2006
This study investigates the potential of adult brain-derived neural precursor cells (NPCs) to promote remyelination and functional recovery after spinal cord injury (SCI) in rats. The researchers tran...
KEY FINDING: Transplanted adult neural precursor cells (NPCs) survived better in the injured spinal cord when transplanted during the subacute phase of injury compared to the chronic phase.
American Journal of Respiratory and Critical Care Medicine, 2006 • March 16, 2006
This case report demonstrates the effectiveness of spinal cord stimulation in restoring cough function in a tetraplegic patient. The technique involves implanting epidural electrodes in the T9, T11, a...
KEY FINDING: Spinal cord stimulation at T9 and L1 levels resulted in airway pressures of 90 and 82 cm H2O, respectively.
BMC Neurology, 2006 • March 15, 2006
This case report describes a 63-year-old woman who presented with progressive triplegia following a road traffic accident, initially raising suspicion for cervical spinal cord injury. However, further...
KEY FINDING: The patient's symptoms of progressive triplegia initially suggested cervical spinal cord injury, but detailed evaluation revealed a cerebrovascular etiology.
J Appl Physiol, 2006 • March 1, 2006
This study evaluated three mathematical models for predicting the force of electrically stimulated paralyzed muscles in individuals with chronic spinal cord injury (SCI). The models included a linear ...
KEY FINDING: Nonlinear models more accurately predicted paralyzed muscle force-time profiles than the linear model.
Spine (Phila Pa 1976), 2006 • March 1, 2006
This study examined the effect of electrically induced muscle contractions on bone mineral density (BMD) decline in individuals with spinal cord injury (SCI). Six individuals with complete paralysis u...
KEY FINDING: The percent decline in BMD for the trained tibia (~10%) was significantly less than the untrained tibia (~25%).
Glia, 2006 • March 1, 2006
This study investigates the neuroprotective effects of olfactory ensheathing cell (OEC) transplantation on corticospinal tract (CST) neurons after dorsal spinal cord transection in rats. The results d...
KEY FINDING: OEC transplantation reduces the number of apoptotic cortical neurons at 1 week post-transplantation.
Journal of NeuroEngineering and Rehabilitation, 2006 • February 28, 2006
This study examined the effects of powered ankle-foot orthoses on the walking patterns of individuals with incomplete spinal cord injury. The orthoses provided plantar flexion assistance, and the stud...
KEY FINDING: Powered ankle-foot orthoses increased ankle angle at stance push-off compared to passive orthoses.
Neurology, 2006 • February 28, 2006
This multicenter, randomized clinical trial compared body weight-supported treadmill training (BWSTT) to conventional over-ground mobility training (CONT) in patients with incomplete spinal cord injur...
KEY FINDING: No significant differences were found between BWSTT and over-ground training (CONT) groups in terms of FIM-L scores or walking speed at 6 months after SCI.