Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,791-11,800 of 12,052 results
Eur Spine J, 2008 • August 2, 2008
This article reviews the use of electrical stimulation for anatomical and functional recovery in spinal cord injury patients. Functional electrical stimulation (FES) can improve limb mobility and othe...
KEY FINDING: Functional electrical stimulation (FES) can improve mobility and restore other bodily functions lost due to spinal cord injury by stimulating paralyzed muscles.
Arch Phys Med Rehabil, 2008 • August 1, 2008
This study aimed to identify health outcomes associated with elevated mortality risk after SCI, evaluating the association of health outcomes with hazard of mortality after SCI. Cox proportional hazar...
KEY FINDING: Multiple types of health conditions were associated with mortality, including probable major depression, surgeries to repair pressure ulcers, fractures and/or amputations, symptoms of infections, and days hospitalized.
Exp Neurol, 2008 • August 1, 2008
This study investigates the urodynamic mechanisms underlying the incomplete recovery of voiding efficiency (VE) following implantation of avulsed lumbosacral ventral roots into the rat conus medullari...
KEY FINDING: The implanted series showed reflex bladder contractions with a significantly shortened urine expulsion phase compared to sham-operated controls.
JOURNAL OF NEUROTRAUMA, 2008 • August 1, 2008
This study investigated the effects of varied implant architectures on spinal cord (SC) regeneration using 3D-printed scaffolds with five different macro-architectures: cylinder, tube, channel, open-p...
KEY FINDING: Open-path scaffold architectures enhanced spinal cord regeneration compared to the three other designs without the use of biological factors.
Pain, 2008 • July 31, 2008
This study investigated the role of TNF signaling in the development of CRPS-like changes in rats after tibia fracture. The researchers found that TNF expression was upregulated in the hindpaw skin an...
KEY FINDING: Tibia fracture upregulated TNF expression and protein levels in the hindpaw skin and sciatic nerve.
PLoS Biology, 2008 • July 22, 2008
The study uses genetic fate mapping to show that ependymal cells lining the central canal of the adult spinal cord act as neural stem cells in vitro and contribute extensively to the glial scar in viv...
KEY FINDING: Close to all in vitro neural stem cell potential in the adult spinal cord resides within the population of ependymal cells lining the central canal.
J. Anat., 2008 • July 21, 2008
This study investigates the therapeutic potential of bone marrow stromal cells (BMSCs) for treating cerebral stroke in rats. BMSCs were transplanted into the cerebrum of rats following a transient mid...
KEY FINDING: Transplanted BMSCs survived and migrated to areas around the lesion site in the rat brains.
Eur Spine J, 2008 • July 18, 2008
The study evaluated the cost-effectiveness of percutaneous vertebroplasty (PVT) compared to conservative medical therapy (CMT) for acute osteoporotic vertebral fractures. PVT showed superior short-ter...
KEY FINDING: PVT resulted in a significantly greater reduction in pain and improvement in ambulation and activities of daily living at 1 week and 3 months compared to CMT.
The Journal of Neuroscience, 2008 • July 16, 2008
This study demonstrates that step training, combined with epidural stimulation and quipazine, leads to a unique locomotor pattern in adult spinal rats. The trained rats showed improved stepping abilit...
KEY FINDING: Trained rats exhibited higher and longer steps compared to nontrained rats.
The Journal of Clinical Investigation, 2008 • July 1, 2008
This study demonstrates that human olfactory ensheathing cells/olfactory nerve fibroblasts (hOECs/ONFs) promote neuroplasticity in murine models of stroke by secreting trophic factors and upregulating...
KEY FINDING: hOECs/ONFs secrete trophic factors, including SDF-1α, and upregulate CXCR4 under oxygen glucose deprivation (OGD) conditions, promoting neurite outgrowth of primary cortical neurons.