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  4. Cost-effectiveness of percutaneous vertebroplasty in osteoporotic vertebral fractures

Cost-effectiveness of percutaneous vertebroplasty in osteoporotic vertebral fractures

Eur Spine J, 2008 · DOI: 10.1007/s00586-008-0708-8 · Published: July 18, 2008

HealthcareMedical ImagingOrthopedics

Simple Explanation

This study examines the effectiveness and cost of percutaneous vertebroplasty (PVT) compared to conservative medical therapy (CMT) for treating osteoporotic vertebral fractures. Patients with refractory pain were offered either PVT or CMT. The study then measured pain levels, mobility, and activities of daily living after both treatments. The results indicated that PVT was initially more effective in reducing pain and improving function, but over 12 months, the differences between the two treatments became less significant.

Study Duration
12 Months
Participants
179 patients (48 males, 131 females)
Evidence Level
Not specified

Key Findings

  • 1
    PVT resulted in a significantly greater reduction in pain and improvement in ambulation and activities of daily living at 1 week and 3 months compared to CMT.
  • 2
    There were no statistically significant differences in cost-effectiveness between the two groups at 12 months.
  • 3
    PVT was significantly more cost-effective than CMT at 1 week with regards to pain, ambulation, and ADL scales.

Research Summary

The study evaluated the cost-effectiveness of percutaneous vertebroplasty (PVT) compared to conservative medical therapy (CMT) for acute osteoporotic vertebral fractures. PVT showed superior short-term results in pain reduction and functional improvement, but long-term outcomes were similar to CMT. The authors conclude that PVT can be considered a valid therapeutic option for patients with refractory pain from osteoporotic vertebral fractures.

Practical Implications

Treatment Choice

PVT may be considered as a first-line treatment for patients with acute osteoporotic vertebral fractures and refractory pain.

Cost Considerations

While PVT demonstrates higher initial cost-effectiveness, long-term benefits may not justify the higher cost compared to CMT.

Clinical Practice

The findings suggest a need for individualized treatment plans considering both clinical effectiveness and economic factors.

Study Limitations

  • 1
    Single-center study
  • 2
    Non-randomized patient enrollment
  • 3
    Retrospective study design

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