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  4. Role of electrical stimulation for rehabilitation and regeneration after spinal cord injury: an overview

Role of electrical stimulation for rehabilitation and regeneration after spinal cord injury: an overview

Eur Spine J, 2008 · DOI: 10.1007/s00586-008-0729-3 · Published: August 2, 2008

Spinal Cord InjuryNeurologyRehabilitation

Simple Explanation

Spinal cord injuries disrupt nerve signals, leading to loss of bodily functions. Electrical stimulation, like FES, can help improve mobility and other functions by stimulating paralyzed muscles. Electrical stimulation can also promote nerve regeneration. Weak direct current fields can encourage neurites to grow towards the cathode, while oscillating fields promote growth in both directions. This article summarizes how electrical stimulation is used for both rehabilitation and nerve regeneration after spinal cord injuries, highlighting the level of recovery achieved in each application.

Study Duration
Not specified
Participants
Not specified
Evidence Level
Overview article

Key Findings

  • 1
    Functional electrical stimulation (FES) can improve mobility and restore other bodily functions lost due to spinal cord injury by stimulating paralyzed muscles.
  • 2
    Weakly applied direct current fields can promote regeneration of neurites towards the cathode, while oscillating field stimulation can promote bidirectional regeneration.
  • 3
    FES devices have therapeutic applications like cardiovascular conditioning and prevention of muscular atrophy, as well as functional applications like ambulation, respiration assistance, and bowel/bladder control.

Research Summary

This article reviews the use of electrical stimulation for anatomical and functional recovery in spinal cord injury patients. Functional electrical stimulation (FES) can improve limb mobility and other body functions by applying controlled electrical stimulus to generate contractions in paralyzed muscles. Weakly applied direct current fields and oscillating field stimulation can promote regeneration of injured nerve fibers.

Practical Implications

Improved Rehabilitation Techniques

FES can be used to develop new rehabilitation techniques that improve mobility and other functions in SCI patients.

Regenerative Therapies

Electrical stimulation can be used as a neuro-regenerative strategy.

Neuroprosthetic Devices

FES devices can be used to develop neuroprosthetic devices.

Study Limitations

  • 1
    FES alone has multiple inherent limitations and requires further research to restore lost function safely and completely.
  • 2
    Most studies evaluating FES-assisted walking have small sample sizes and short follow-up times, limiting the data available.
  • 3
    OFS is an invasive intervention with multiple risks, and the true extent of neurological recovery associated with OFS alone cannot be assessed.

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