Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 11-20 of 702 results
Neural Regeneration Research, 2014 • November 1, 2014
This article systematically reviews and analyzes various kinds of animal models of spinal cord injury and assesses their advantages and disadvantages for further studies. SCI animal models, including ...
KEY FINDING: Rodent models offer advantages such as well-described methods for reproducible SCI and widely available behavioral outcome measures. However, clinical trials based on rodent studies have often failed to demonstrate convincing efficacy, potentially due to differences between rodent and human SCI.
Neural Regen Res, 2012 • June 1, 2012
This study used bibliometric analyses to quantitatively and qualitatively investigate research trends in studies of stem cell transplantation for treating spinal cord injury. BMMSCs and ESCs are widel...
KEY FINDING: Bone marrow mesenchymal stem cells (BMMSCs) and embryonic stem cells (ESCs) are widely studied for treating spinal cord injury.
Neural Regeneration Research, 2015 • January 1, 2015
This study introduces a novel goat model for cauda equina injury and repair, addressing the limitations of rat models. The goat model allows for surgical repair and monitoring of outcomes using electr...
KEY FINDING: The study successfully established a goat experimental model that mimics human cauda equina injury, allowing for surgical repair and outcome monitoring.
Global Spine Journal, 2025 • June 27, 2024
This systematic review and meta-analysis evaluated the utility of diffusion tensor imaging (DTI) in diagnosing and assessing degenerative cervical myelopathy (DCM). It analyzed 57 studies involving ov...
KEY FINDING: Fractional anisotropy (FA) values are significantly lower in DCM patients compared to healthy subjects at the maximal compression level.
Anim Models Exp Med, 2025 • January 1, 2025
The study established a rat model of spinal cord compression and decompression to investigate SCII following decompressive cervical laminectomy. The model showed that spinal cord decompression leads t...
KEY FINDING: Spinal cord compression led to abnormal mechanical pain and decreased forepaw grip strength in rats.
European Urology Open Science, 2024 • October 3, 2024
This systematic review and meta-analysis aimed to investigate the incidence of and risk factors for urinary stones in patients with spinal cord injury (SCI). The study found a high incidence of urinar...
KEY FINDING: The overall incidence of urinary stones after SCI was found to be 16.6%.
BMJ Case Rep, 2024 • November 6, 2024
This case report describes the clinical journey of a male patient in early childhood with developmental delay, failure to thrive, worsening right-sided head tilt torticollis and regression of motor s...
KEY FINDING: Torticollis can be an early sign of basilar invagination (BI) in children, which requires thorough diagnostic evaluation.
Journal of Medical Case Reports, 2024 • November 23, 2024
This case report describes a rare instance of spinal schwannoma presenting with intraspinal hematoma in a 53-year-old female. The patient experienced sudden lower limb pain, necessitating emergency su...
KEY FINDING: The patient presented with a T12 schwannoma accompanied by an intratumoral hematoma, experiencing sudden and unbearable pain in the lower limbs.
Frontiers in Pharmacology, 2024 • December 11, 2024
This study provides a bibliometric analysis of nanotechnology in SCI research, highlighting global research output, collaborative networks, and influential works. The analysis identifies China, the Un...
KEY FINDING: China and the United States are the leading countries in nanotechnology research for SCI, with China showing rapid growth in publications after 2019.
World Journal of Orthopedics, 2024 • December 18, 2024
This case report presents a unique instance of a 15-year-old male developing acute cervical spine pyogenic infection (CSPI) secondary to chronic paronychia caused by Staphylococcus aureus. The patient...
KEY FINDING: The study highlights a rare case of cervical spine pyogenic infection (CSPI) stemming from chronic paronychia, emphasizing that infections can originate from unexpected sources.