Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 151-160 of 702 results
J Neurosci Methods, 2016 • September 1, 2016
The study introduces a method to enhance FG uptake using Triton™, reducing FG-related tissue damage while maintaining effective quantification. Triton™ enhances FG uptake, reduces required FG, and sub...
KEY FINDING: Triton™ decreases the time required for long-distance transport of FG from the spinal cord to the motor cortex by >4 fold.
Biochem Biophys Res Commun, 2018 • February 19, 2018
This study investigates the role of Wnt/β-catenin signaling in fibrotic scar formation following spinal cord injury (SCI) in adult mice using a compression-SCI model and TOPgal reporter mice. The resu...
KEY FINDING: Wnt/β-catenin signaling reporter TOPgal positive cells appeared at the lesion site by 5 days, peaked on 7 days, and diminished by 14 days post injury.
The Journal of Spinal Cord Medicine, 2024 • March 1, 2023
This multi-center study validated the Spinal Cord Independence Measure version IV (SCIM IV) using Rasch analysis, demonstrating its reliability and validity for assessing daily task execution in indiv...
KEY FINDING: SCIM IV subscale scores are reliable and valid based on Rasch analysis.
Spinal Cord Series and Cases, 2024 • July 18, 2024
This case series describes five patients with non-surgical spinal cord infarction, detailing their initial presentations and functional outcomes after long-term follow-up (mean 6.5 years). The study f...
KEY FINDING: Severity of initial presentation correlates with long-term functional outcomes. Cases with more neurological impairment at the start had greater disability at follow-up.
Global Spine Journal, 2024 • February 1, 2024
The study aimed to address the inconsistency in the naming and definition of cervical myelopathy caused by degenerative changes to the spine. Through a structured, iterative consensus process involvin...
KEY FINDING: The study selected 'Degenerative Cervical Myelopathy' (DCM) as the unifying term for the condition.
J. Clin. Med., 2024 • January 1, 2024
This study evaluated the use of Artificial Neural Networks (ANNs) to predict the prognosis of patients with cervical spinal cord injury (SCI) using acute-phase clinical data. The ANNs model outperform...
KEY FINDING: ANNs predicted the prognosis of patients with cervical SCI more accurately than MLR analysis (75.0% vs 31.3%).
Spinal Cord, 2024 • May 1, 2024
This qualitative study explored the knowledge, perceptions, and beliefs about UTIs among Veterans with neurogenic bladder (NB) to inform the development of person-centered interventions for improved U...
KEY FINDING: Participants showed knowledge gaps in UTI prevention, identifying specific UTI symptoms, and understanding antibiotic side effects.
Turk J Phys Med Rehab, 2024 • July 2, 2024
The study successfully adapted the Spinal Cord Injury Secondary Conditions Scale (SCI-SCS) for use in the Turkish population. The Turkish SCI-SCS demonstrated good reliability and validity, making it ...
KEY FINDING: The Turkish version of the SCI-SCS showed good internal consistency and excellent test-retest reliability, indicating it is a reliable tool.
The Journal of Spinal Cord Medicine, 2023 • May 1, 2023
This study prospectively evaluated the clinical utility of the van Middendorp clinical prediction rule (CPR) among physical therapists working with individuals with spinal cord injuries and disorders ...
KEY FINDING: Clinical utility was reported for 45% of those with SCI and 88% with non-traumatic SCI/D.
The Journal of Spinal Cord Medicine, 2023 • July 1, 2023
The main finding from this study was that sport facilitates the progression to living an enriching life with SCI. The extensive benefits of sport included improvements in strength, independence, menta...
KEY FINDING: Sport facilitates the progression to living an enriching life with SCI.