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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 161-170 of 702 results

Spinal Cord InjurySurgeryResearch Methodology & Design

A Clinical Practice Guideline for Prevention, Diagnosis and Management of Intraoperative Spinal Cord Injury: Recommendations for Use of Intraoperative Neuromonitoring and for the Use of Preoperative and Intraoperative Protocols for Patients Undergoing Spine Surgery

Global Spine Journal, 2024 • March 1, 2024

These guidelines recommend intraoperative neurophysiologic monitoring for high-risk patients undergoing spine surgery to detect and manage intraoperative spinal cord injury. The guidelines suggest ide...

KEY FINDING: Intraoperative neurophysiologic monitoring is recommended for high-risk patients undergoing spine surgery, based on a review of 164 studies.

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Spinal Cord InjuryCOVID-19Research Methodology & Design

“It’s been a double-edged sword”: An online qualitative exploration of the impact of COVID- 19 on individuals with spinal cord injury in the US with comparisons to previous UK findings

The Journal of Spinal Cord Medicine, 2024 • January 1, 2024

This paper represents a novel exploration of the experiences of people living with SCI in response to the COVID-19 pandemic and subsequent restrictions put in place to manage the outbreak across the U...

KEY FINDING: Participants experienced challenges in health and access to care, including cancelled appointments, delayed procedures, and difficulties accessing necessary medical supplies and caregivers.

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Spinal Cord InjuryEndocrinologyResearch Methodology & Design

Physical and emotional consequences of excess weight as experienced by individuals with spinal cord injuries

The Journal of Spinal Cord Medicine, 2024 • January 1, 2024

This study used qualitative interviews to explore the consequences of excess weight from the perspective of individuals with SCI. Five key themes emerged: physical health conditions, physical symptoms...

KEY FINDING: Excess weight leads to physical health conditions such as chronic diseases and SCI secondary complications.

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Spinal Cord InjuryPediatricsResearch Methodology & Design

Lived experiences of caregivers and survivors of paediatric spinal cord injury: A scoping review of qualitative studies

The Journal of Spinal Cord Medicine, 2024 • January 1, 2024

This scoping review aimed to explore what is known about the lived experiences of survivors and caregivers of paediatric SCI. There was a lack of accessible environments and specialised rehabilitation...

KEY FINDING: Caregivers face obstacles to community participation, unmet needs related to their child's SCI, and radiating effects on their own lives, including stress and financial difficulties.

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Spinal Cord InjuryMental HealthResearch Methodology & Design

ICF-linking and psychometric properties of upper extremity mobility outcome measures in spinal cord injury – a scoping review

The Journal of Spinal Cord Medicine, 2024 • February 1, 2024

This scoping review aimed to explore outcome measures used in upper extremity rehabilitation and research for spinal cord injury, and to investigate their psychometric properties. The review identifie...

KEY FINDING: Four outcome measures (GRASSP, AuSpinal, SHFT, TRI-HFT) and nine psychometric studies were selected.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Predicting outdoor walking one-year after spinal cord injury: a retrospective multisite external validation study

J Neurol Phys Ther, 2023 • July 1, 2023

This study externally validated the Canadian 2021 outdoor walking CPR using data from 12 SCIMS centers in the United States. The study found that a CPR threshold of ≥ 33, based on ISNCSCI sensory and ...

KEY FINDING: The study externally validated a clinical prediction rule (CPR) for predicting outdoor walking ability one year after spinal cord injury (SCI).

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Spinal Cord InjuryCardiovascular ScienceResearch Methodology & Design

A Mouse Model of Spinal Cord Hypoperfusion with Immediate Paralysis Caused by Endovascular Repair of Thoracic Aortic Aneurysm

Anesthesiology, 2023 • April 1, 2023

The study successfully developed a mouse model of spinal cord hypoperfusion induced by ligation of intercostal arteries, mimicking the ischemic spinal cord injury observed in humans after TEVAR. The m...

KEY FINDING: Ligation of intercostal arteries induced a significant and instantaneous drop in blood flow in both the intercostal arteries and the thoracic spinal cord.

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Spinal Cord InjuryHealthcareResearch Methodology & Design

Data and subject heterogeneity and data sharing: keys to translational success in spinal cord injury research?

Neural Regeneration Research, 2023 • August 1, 2023

The perspective discusses the challenges of translating spinal cord injury (SCI) research findings into clinical treatments due to subject heterogeneity and lack of transparency in data reporting. It ...

KEY FINDING: Older mice responded worse to antioxidant treatment after SCI, despite restored glutathione levels and reduced oxidative damage.

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BioinformaticsResearch Methodology & Design

Adjusting for informative cluster size in pseudo-value based regression approaches with clustered time to event data

Stat Med, 2023 • June 15, 2023

The paper addresses the problem of informative cluster size (ICS) in the context of pseudo-value regression for clustered time-to-event data. It explores different strategies for ICS adjustment, inclu...

KEY FINDING: The study identifies appropriate strategies for adjusting for informative cluster size (ICS) in pseudo-value regression analysis.

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Spinal Cord InjurySurgeryResearch Methodology & Design

An Update of a Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role and Timing of Decompressive Surgery

Global Spine Journal, 2024 • March 1, 2024

This clinical practice guideline (CPG) updates the 2017 recommendations on the timing of surgical decompression for acute spinal cord injury (SCI), evaluating evidence for early (≤24 hours) and ultra-...

KEY FINDING: The guideline recommends that early surgery (within 24 hours of injury) should be considered for adult patients with acute spinal cord injury, no matter the severity or location of the injury.

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