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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 581-590 of 682 results

Pain ManagementRehabilitation

Neural mobilization reverses behavioral and cellular changes that characterize neuropathic pain in rats

Molecular Pain, 2012 • July 29, 2012

This study investigates the effects of neural mobilization (NM) on pain sensitivity in rats with chronic constriction injury (CCI). The results show that NM treatment reduces hyperalgesia and allodyni...

KEY FINDING: Neural mobilization treatment induced an early reduction of hyperalgesia and allodynia in CCI-injured rats, which persisted until the end of the treatment.

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Spinal Cord InjuryNeurologyPain Management

Central nociceptive sensitization vs. spinal cord training: opposing forms of plasticity that dictate function after complete spinal cord injury

Frontiers in Physiology, 2012 • October 4, 2012

The experiments were designed to test for cross-talk between spinal training and nociceptive plasticity in complete SCI. The results indicate that spinal training history can influence future nocicepti...

KEY FINDING: Spinal training history influences future nociceptive responsiveness to formalin. Specifically, uncontrollable stimulation enhances tactile hyper-reactivity.

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Spinal Cord InjuryPain ManagementMedical Imaging

Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury

Pain, 2013 • February 1, 2013

This study investigated the relationship between metabolite concentrations in the anterior cingulate cortex (ACC) and neuropathic pain after spinal cord injury (SCI). The study revealed that individua...

KEY FINDING: The SCI-HPI group had significantly higher levels of myoinositol (Ins), creatine, and choline, and significantly lower levels of N-acetyl aspartate/Ins and glutamate-glutamine (Glx)/Ins ratios than the SCI-LPI group.

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Mental HealthNeurologyPain Management

Psychological Screening/Phenotyping as Predictors for Spinal Cord Stimulation

Curr Pain Headache Rep, 2013 • January 1, 2013

Psychological screening and QST can help predict SCS outcomes. Psychological factors such as depression and anxiety are key predictors of success. QST measures, including pain thresholds and temporal ...

KEY FINDING: Psychological factors like somatization, depression, and anxiety are strong predictors of poor response to spinal cord stimulation.

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NeurologyPain ManagementRehabilitation

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

Journal of Visualized Experiments, 2013 • January 10, 2013

Breathing-controlled electrical stimulation (BreEStim) has demonstrated clinical efficacy in spasticity management and subsequent hand function recovery in chronic stroke patients, as well as manageme...

KEY FINDING: BreEStim effectively reduced finger flexor spasticity in a post-stroke patient, improving hand function, with benefits lasting for at least eight weeks.

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Mental HealthNeurologyPain Management

Acceptance of Pain in Neurological Disorders: Associations With Functioning and Psychosocial Well-Being

Rehabil Psychol, 2013 • February 1, 2013

This study examined the role of pain acceptance in individuals with chronic pain secondary to neurological disorders. The research indicated that activity engagement, a component of pain acceptance, w...

KEY FINDING: Activity engagement predicted lower pain interference and depression, and greater quality of life and social role satisfaction.

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Spinal Cord InjuryPain ManagementResearch Methodology & Design

Proposed International Spinal Cord Injury Pain (ISCIP) Classification: Preliminary Validation Data

Top Spinal Cord Inj Rehabil, 2012 • January 1, 2012

This study assessed the reliability of the ISCIP classification among clinicians with minimal training, using clinical vignettes. The results showed moderate reliability, with some pain subtypes being...

KEY FINDING: Respondents showed high confidence in identifying the number of pain components, with an average correctness of 86%.

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Spinal Cord InjuryPharmacologyPain Management

Effects of Nicotine on Spinal Cord Injury Pain: A Randomized, Double-Blind, Placebo Controlled Crossover Trial

Top Spinal Cord Inj Rehabil, 2012 • January 1, 2012

This study examined the effects of nicotine on different subtypes of pain following SCI, using a randomized, placebo-controlled crossover trial. The results indicated differential effects of nicotine ...

KEY FINDING: Nonsmokers with SCI experienced a reduction in mixed forms of pain following nicotine exposure.

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Spinal Cord InjuryMental HealthPain Management

Psychometric evaluation of the Spanish version of the MPI-SCI

Spinal Cord, 2013 • July 1, 2013

The study confirmed the factor structure of the Spanish version of the MPI-SCI and tested its internal consistency and construct validity in a Spanish population with SCI and chronic pain. The MPI-SCI...

KEY FINDING: Confirmatory factor analysis suggested an adequate factor structure for the MPI-SCI-S.

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Spinal Cord InjuryPain ManagementRehabilitation

Neuropathic Pain Post Spinal Cord Injury Part 1: Systematic Review of Physical and Behavioral Treatment

Top Spinal Cord Inj Rehabil, 2013 • January 1, 2013

This systematic review assessed the effectiveness of nonpharmacological treatments for neuropathic pain post-SCI, focusing on physical and behavioral therapies. The review included 16 studies and foun...

KEY FINDING: Transcranial electrical stimulation (TES) shows the strongest evidence for reducing neuropathic pain after SCI, based on multiple RCTs.

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