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  4. Neuropathic Pain Post Spinal Cord Injury Part 1: Systematic Review of Physical and Behavioral Treatment

Neuropathic Pain Post Spinal Cord Injury Part 1: Systematic Review of Physical and Behavioral Treatment

Top Spinal Cord Inj Rehabil, 2013 · DOI: 10.1310/sci1901-61 · Published: January 1, 2013

Spinal Cord InjuryPain ManagementRehabilitation

Simple Explanation

Neuropathic pain is a common and persistent problem after spinal cord injury (SCI), impacting quality of life. It is often managed with both medications and non-drug treatments. This review examines the effectiveness of physical (e.g., electrical stimulation, acupuncture) and behavioral (e.g., cognitive therapy, hypnosis) therapies for neuropathic pain in SCI. The study found varying levels of evidence for different non-drug treatments, with some showing promise in reducing pain or improving coping, but more research is needed.

Study Duration
Not specified
Participants
433 participants
Evidence Level
Mixed levels (1, 2, and 4)

Key Findings

  • 1
    Transcranial electrical stimulation (TES) shows the strongest evidence for reducing neuropathic pain after SCI, based on multiple RCTs.
  • 2
    Combined osteopathic treatment and pregabalin provide greater pain relief than either treatment alone.
  • 3
    Behavioral pain management programs may improve mood, coping, and sleep quality, but do not consistently reduce neuropathic pain levels.

Research Summary

This systematic review assessed the effectiveness of nonpharmacological treatments for neuropathic pain post-SCI, focusing on physical and behavioral therapies. The review included 16 studies and found varying levels of evidence for different interventions, with transcranial electrical stimulation showing the most promise. The authors conclude that while some nonpharmacological therapies may offer benefits, further research is needed to establish their efficacy and optimal application for SCI-related neuropathic pain.

Practical Implications

Clinical Practice

Consider transcranial electrical stimulation (TES) as a potential non-pharmacological treatment option for neuropathic pain in SCI patients.

Combined Therapies

Explore the use of combined osteopathic and pharmacological interventions for enhanced pain relief.

Psychological Support

Offer behavioral pain management programs to address mood and coping difficulties associated with chronic pain, even if pain reduction is not guaranteed.

Study Limitations

  • 1
    Small sample sizes in many included studies.
  • 2
    Heterogeneity in study designs and outcome measures.
  • 3
    Lack of control groups in some studies.

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