Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 501-510 of 682 results
Drug Design, Development and Therapy, 2020 • December 4, 2020
This study investigates the effect of sanguinarine (SG) on chronic constriction injury (CCI)-induced neuropathic pain (NP) in rats. SG is a natural plant medicine known for its anti-inflammatory and n...
KEY FINDING: Sanguinarine (SG) treatment increased paw withdrawal mechanical threshold (PWT) and thermal withdrawal latency (TWL) in CCI rats, indicating reduced mechanical sensitivity and heat hypersensitivity.
The Journal of Spinal Cord Medicine, 2017 • January 1, 2017
The study explores medical complications, particularly pain, and their relation to poor sleep in individuals with pediatric-onset SCI. It also examines the connection between sleep quality, activity l...
KEY FINDING: Pain in specific locations such as the neck, shoulder, arm/elbow, and lower extremities increases the odds of poor sleep.
Spinal Cord, 2005 • May 1, 2005
The study examined how pain changes during recovery from spinal cord injury (SCI) and its relationship with community integration. A significant proportion of individuals with SCI reported pain at 6 m...
KEY FINDING: 86% of individuals with SCI reported pain at 6 months post-discharge, with 27% reporting pain impacting many or most activities.
Clin J Pain, 2018 • April 1, 2018
This study investigated the relationship between pain acceptance and medication use in individuals with chronic pain and spinal cord injury (SCI). The results indicated that higher pain acceptance is ...
KEY FINDING: Higher pain acceptance was related to a significantly lower number of pain medications used, even when considering pain intensity, the number of painful body areas, and depressive symptoms.
BMC Medical Research Methodology, 2005 • October 4, 2005
This cross-sectional study examined the interchangeability of the Visual Analogue Scale (VAS) and the Verbal Rating Scale (VRS) in assessing pain intensity among patients with chronic/idiopathic, noci...
KEY FINDING: There was an overlapping of VAS records relative to the VRS categories in all pain groups, indicating a lack of direct correspondence between the two scales.
J Headache Pain, 2005 • December 15, 2005
This case report describes a 26-year-old woman with post-traumatic cervicogenic headache treated with cervical cord stimulation after failing medical and surgical interventions. The patient experience...
KEY FINDING: Cervical cord stimulation was effective in improving cervicogenic headache in a patient who had undergone cervical discectomy and fusion.
Molecular Pain, 2006 • April 3, 2006
The study investigated the role of PKC in spinal cord in mediating chronic injury-induced pain and its relationship with glutamate receptors. Activation of PKC in the spinal cord produces mechanical h...
KEY FINDING: Intrathecal injection of PDBu (phorbol 12,13 dibutyrate) decreased the mechanical withdrawal threshold bilaterally in a dose-dependent manner, indicating increased sensitivity to pain.
Brain Res., 2007 • March 9, 2007
Increases in extracellular GABA in the L3/L4 spinal cord occur in response to high frequency TENS, but not low frequency TENS. Blockade of GABAA in the spinal cord reduced the antihyperalgesia produce...
KEY FINDING: High frequency TENS increases extracellular GABA concentrations in the spinal cord in animals with and without joint inflammation.
Clin J Pain, 2018 • February 1, 2018
This study evaluated the effectiveness of the Vancouver Acute Neuropathic Pain Treatment Guideline (VANPTG) in assessing and diagnosing neuropathic pain (NP) in patients with traumatic spinal cord inj...
KEY FINDING: The incidence of NP was 56% in patients with traumatic SCI during acute hospital care.
Journal of Orthopaedic Surgery and Research, 2017 • March 24, 2017
This study investigates the roles of iron overload and subsequent microglia activation in the remodeling of the brain after SCI. The results indicate that after SCI, activation of IRP can lead to intr...
KEY FINDING: SCI induces intracranial iron overload, especially in the hindlimb sensory area, hippocampus, and thalamus.