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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 511-520 of 682 results

Spinal Cord InjuryPharmacologyPain Management

Effectiveness of amitriptyline and lamotrigine in neuropathic pain after traumatic spinal cord injuries

Spinal Cord Series and Cases, 2017 • May 18, 2017

This correspondence critically evaluates a study comparing amitriptyline and lamotrigine for neuropathic pain after spinal cord injury. The authors highlight the scarcity of direct comparisons between...

KEY FINDING: The original study by Agarwal and Joshi reports the effectiveness of amitriptyline and lamotrigine in neuropathic pain after traumatic spinal cord injuries.

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NeurologyPain ManagementGenetics

Is Functional State of Spinal Microglia Involved in the Anit-allodynic and Anti-hyperalgesic Effects of Electroacupuncture in Rat Model of Monoarthritis?

Neurobiol Dis, 2007 • June 1, 2007

This study investigates the role of spinal microglia in the anti-allodynic and anti-hyperalgesic effects of electroacupuncture (EA) in a rat model of monoarthritis induced by Complete Freund’s Adjuvan...

KEY FINDING: Unilateral intra-articular injection of CFA produced a robust microglial activation and the up-regulation of the tumor necrosis factor (TNF)-α, interleukin (IL-1β), and IL-6 mRNA levels in the spinal cord.

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Pain ManagementGenetics

TNF signaling contributes to the development of nociceptive sensitization in a tibia fracture model of complex regional pain syndrome type I

Pain, 2008 • July 31, 2008

This study investigated the role of TNF signaling in the development of CRPS-like changes in rats after tibia fracture. The researchers found that TNF expression was upregulated in the hindpaw skin an...

KEY FINDING: Tibia fracture upregulated TNF expression and protein levels in the hindpaw skin and sciatic nerve.

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Spinal Cord InjuryPain ManagementRehabilitation

Pain intensity, pain interference and characteristics of spinal cord injury

Spinal Cord, 2008 • June 1, 2008

This study examined the prevalence, intensity, and interference of pain in individuals with spinal cord injury (SCI). It investigated the relationship between pain characteristics and patient demograp...

KEY FINDING: Persons with higher level injuries were more likely to report upper extremity pain than persons with paraplegic injuries.

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Spinal Cord InjuryMental HealthPain Management

Pain Catastrophizing and Beliefs Predict Changes in Pain Interference and Psychological Functioning in Persons with Spinal Cord Injury

J Pain, 2008 • September 1, 2008

This study examined the longitudinal relationships between pain-related beliefs, coping, and social support with pain interference and psychological functioning in individuals with spinal cord injury ...

KEY FINDING: Changes in catastrophizing were significantly associated with changes in pain interference and psychological functioning; increased catastrophizing predicted greater pain interference and poorer psychological functioning.

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AgingNeurologyPain Management

Coping With Chronic Pain Among Younger, Middle-Aged, and Older Adults Living With Neurological Injury and Disease

J Aging Health, 2008 • January 1, 2008

This study investigated age-related differences in pain coping strategies among adults with chronic pain secondary to disability. The study found that older adults used a wider range of coping strateg...

KEY FINDING: Older adults reported a wider range of frequently used strategies and significantly more frequent engagement in activity pacing, seeking social support, and use of coping self-statements than did younger or middle-aged adults.

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Spinal Cord InjuryAlternative MedicinePain Management

Effects of Self-Hypnosis Training and Emg Biofeedback Relaxation Training on Chronic Pain in Persons with Spinal-Cord Injury

Int J Clin Exp Hypn, 2009 • July 1, 2009

The study compared self-hypnosis (HYP) and EMG biofeedback (BIO) for chronic pain management in spinal cord injury (SCI) patients, finding both reduced immediate pain. HYP group showed lasting daily p...

KEY FINDING: Participants in both treatment conditions reported substantial, but similar, decreases in pain intensity from before to after the treatment sessions.

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Alternative MedicineNeurologyPain Management

Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism

Pain, 2009 • October 1, 2009

The study investigated the analgesic effects of electroacupuncture (EA) on capsaicin-induced secondary hyperalgesia in rats, an animal model representing central sensitization. EA applied to specific ...

KEY FINDING: EA at acupoints SI3-TE8 significantly reduced capsaicin-induced secondary hyperalgesia, but not primary hyperalgesia.

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Spinal Cord InjuryMental HealthPain Management

Reliability and Validity of the International Spinal Cord Injury Basic Pain Dataset Items as Self-Report Measures

Spinal Cord, 2010 • March 1, 2010

This study evaluated the psychometric properties of the International Spinal Cord Injury Basic Pain Data Set (ISCIBPDS) items when used as self-report measures by individuals with spinal cord injury (...

KEY FINDING: The ISCIBPDS items measuring pain interference, intensity, site(s), frequency, duration, and timing are useful and valid for individuals with SCI and chronic pain.

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Spinal Cord InjuryNeurologyPain Management

Effectiveness of transcranial direct current stimulation and visual illusion on neuropathic pain in spinal cord injury

Brain, 2010 • August 4, 2010

This study evaluated the analgesic effect of transcranial direct current stimulation (tDCS) of the motor cortex and visual illusion techniques, applied alone or combined, in patients with neuropathic ...

KEY FINDING: The combination of transcranial direct current stimulation and visual illusion significantly reduced the intensity of neuropathic pain more than any of the single interventions.

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