Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 491-500 of 682 results
Annals of Neurology, 2016 • April 1, 2016
This randomized, double-blind, placebo-controlled study evaluated the analgesic effect of botulinum toxin type A (BTX-A) on neuropathic pain in patients with spinal cord injury (SCI). The study found ...
KEY FINDING: BTX-A significantly reduced pain intensity compared to placebo at both 4 and 8 weeks post-injection, as measured by the Visual Analogue Scale (VAS).
PLoS ONE, 2016 • January 28, 2016
The study used a porcine model to test the effects of thoracolumbar fascia injury and movement restriction on fascia thickness and mobility. Injury alone increased fascia thickness and decreased shear...
KEY FINDING: Injury alone caused an increase in fascia thickness and a decrease in shear strain on the non-injured side.
Cochrane Database of Systematic Reviews, 2017 • January 1, 2017
This overview of Cochrane Reviews examined the effectiveness and safety of physical activity and exercise for chronic pain in adults. The review included 21 Cochrane Reviews encompassing various chron...
KEY FINDING: Several reviews noted favourable results from exercise on pain severity, but the results were inconsistent across interventions and follow-up periods.
Rehabil Psychol, 2016 • February 1, 2016
The study examined the independent contributions of vulnerability and resilience factors to pain-related outcomes in individuals with chronic pain and physical disabilities. Results indicated that res...
KEY FINDING: Both resilience and vulnerability factors significantly contribute to pain outcomes.
The Journal of Spinal Cord Medicine, 2018 • May 1, 2018
This study developed and validated the SCI-QOL Pain Interference item bank and the SCI-QOL Pain Behavior scale, which are optimized for individuals with SCI. The measures were developed using qualitat...
KEY FINDING: The SCI-QOL Pain Interference item bank and the SCI-QOL Pain Behavior scale demonstrated robust psychometric properties.
Journal of Pain Research, 2016 • June 15, 2016
This study explored the relationship between pain relief and improvement in function among patients with SCI-associated NeP. Pain reduction is likely associated with improvement in several different d...
KEY FINDING: Greater functional improvements were generally achieved at higher levels of clinically significant pain reduction.
BMC Neurology, 2017 • March 15, 2017
The study aimed to evaluate the measurement properties of painDETECT (PD-Q) using Rasch analysis to determine its suitability as an outcome measure for neuropathic pain (NeP). The analysis involved da...
KEY FINDING: PD-Q demonstrated fit to the Rasch model after adjustments of scoring categories for four items, and omission of the time course and radiating questions.
MOLECULAR MEDICINE REPORTS, 2017 • January 1, 2017
The study aimed to investigate gene alterations in patients with spinal cord injury (SCI) and to further examine the mechanisms underlying neuropathic pain (NP) following SCI. A total of 70 upregulate...
KEY FINDING: A total of 70 upregulated and 61 downregulated DEGs were identified in the PBMC samples from patients with NP.
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This case report demonstrates the feasibility and potential benefits of using percutaneous PNS to treat chronic shoulder pain in an individual with SCI. The subject experienced a reduction in pain and...
KEY FINDING: The subject experienced a 44% reduction in worst pain one week after the end of treatment, as measured by the BPI-SF3 scale.
Molecular Pain, 2017 • January 1, 2017
The study investigated dendritic spine remodeling in lamina II neurons after spinal cord injury (SCI) in rats exhibiting neuropathic pain. Results showed an inverse relationship between thin- and mush...
KEY FINDING: Total density of dendritic spines on lamina II neurons did not change after spinal cord injury.