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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Musculoskeletal Medicine Research

Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.

Showing 81-90 of 278 results

Spinal Cord InjuryNeurologyMusculoskeletal Medicine

Vertebral insufficiency fractures as a cause of autonomic dysreflexia in a patient with chronic tetraplegia: A case report

The Journal of Spinal Cord Medicine, 2022 • October 28, 2020

This case report describes multiple thoracic and lumbar vertebral compression fractures in a patient with chronic motor incomplete tetraplegia, highlighting a less common complication of SCI. The pati...

KEY FINDING: A patient with chronic SCI presented with new-onset autonomic dysreflexia and spasticity.

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Spinal Cord InjuryPatient ExperienceMusculoskeletal Medicine

Lower extremity fracture prevention and management in persons with spinal cord injuries and disorders: The patient perspective

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This study describes perspectives of patients with SCI/D on fracture prevention and management and revealed a range of knowledge about osteoporosis and awareness of when a fracture occurred. Participa...

KEY FINDING: Participants expressed concerns about bone health and fractures, which limited activities and participation for some.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Skeletal muscle stiffness as measured by magnetic resonance elastography after chronic spinal cord injury: a cross-sectional pilot study

Neural Regen Res, 2021 • December 1, 2021

The study investigated muscle stiffness in individuals with chronic SCI using magnetic resonance elastography (MRE) and compared it to able-bodied controls. The results indicated a trend of lower musc...

KEY FINDING: Muscle stiffness was non-significantly lower in the SCI group compared to able-bodied controls.

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RheumatologyResearch Methodology & DesignMusculoskeletal Medicine

Atraumatic thoracic spinal fracture mimicking herpes zoster neuralgia: a case report

J Med Case Reports, 2021 • May 10, 2021

This case report describes a 70-year-old man with ankylosing spondylitis who presented with severe intercostal neuralgia, initially misdiagnosed as herpes zoster. Further investigation revealed an atr...

KEY FINDING: Severe intercostal neuralgia can be an early symptom of atraumatic spinal fractures in patients with ankylosing spondylitis.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Peak Torque Prediction Using Handgrip and Strength Predictors in Men and Women With Motor Complete Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2021 • July 1, 2021

The study established predictive equations for peak torque of muscle groups with totally and partially preserved innervation in individuals with motor complete SCI. Handgrip strength was found to be a...

KEY FINDING: Handgrip strength was a significant predictor of shoulder abduction and adduction peak torque.

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Spinal Cord InjuryPharmacologyMusculoskeletal Medicine

Pharmacologic approaches to prevent skeletal muscle atrophy after spinal cord injury

Curr Opin Pharmacol, 2021 • October 1, 2021

Severe SCI leads to rapid muscle atrophy due to neural insult, paralysis, systemic inflammation, hormonal imbalances, and glucocorticoid treatment. The review discusses the SCI muscle phenotype, molec...

KEY FINDING: Muscle loss after SCI is more rapid than in other disuse conditions, with distinct molecular signaling cascades.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Handgrip Strength Cutoff Points for Functional Independence and Wheelchair Ability in Men With Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2021 • September 1, 2021

This study determined optimal handgrip strength (HGS) cutoff points for greater functional independence and wheelchair skills in men with spinal cord injury (SCI). The HGS was a significant predictor ...

KEY FINDING: A handgrip strength of 102.5 kgf was identified as a cutoff point to achieve a score of 70 on the Spinal Cord Independence Measure (SCIM-III).

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Brain InjuryPublic HealthMusculoskeletal Medicine

Predictors of Thoracic and Lumbar Spine Injuries in Patients with TBI: A Nationwide Analysis

Injury, 2022 • March 1, 2022

This study used a national trauma database to identify risk factors for concomitant thoracic and lumbar spine fractures in patients with traumatic brain injury (TBI). The analysis revealed that factor...

KEY FINDING: Moderate and severe TBI, as defined by Glasgow Coma Scale (GCS), were significantly associated with both thoracic and lumbar spine fractures.

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Spinal Cord InjuryResearch Methodology & DesignMusculoskeletal Medicine

A multilevel noncontiguous spinal fracture with cervical and thoracic spinal cord injury

International Journal of Surgery Case Reports, 2021 • October 19, 2021

This case report describes the operative management of an 18-year-old male with a multilevel noncontiguous spinal fracture (MNSF) and spinal cord injury involving the cervical and thoracic vertebrae. ...

KEY FINDING: MNSF with spinal cord injury following high-velocity accidents are unstable and complex injuries.

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Spinal Cord InjuryBioinformaticsMusculoskeletal Medicine

The use of alkaline phosphatase as a bone turnover marker after spinal cord injury: A scoping review of human and animal studies

The Journal of Spinal Cord Medicine, 2023 • March 1, 2023

The review highlights the potential utility of ALP and B-ALP in assessing changes in bone turnover in humans with SCI, but evidence in animal models is less compelling. The association between ALP and...

KEY FINDING: Evidence regarding changes in ALP levels in individuals with SCI compared to controls is conflicting.

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