Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 71-80 of 278 results
Molecular Medicine, 2024 • November 7, 2024
This study investigates the causal relationship between mitochondrial abnormalities and chronic post-sepsis muscle weakness, exploring potential therapeutic targets. The findings demonstrate that post...
KEY FINDING: Post-sepsis skeletal muscle weakness develops progressively after the resolution of acute sepsis and is linked to mitochondrial abnormalities.
SAGE Open Medical Case Reports, 2024 • November 5, 2024
This case report presents the results of multiple dual-energy X-ray absorptiometry scans conducted over 14 years, highlighting changes in bone mineral density (BMD). The individual studied maintained ...
KEY FINDING: An individual with chronic complete SCI maintained and, in some areas, increased BMD in the lower extremities over 14 years.
Cell Reports Medicine, 2024 • December 17, 2024
This study investigates why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles. The central rol...
KEY FINDING: Severe SCI causes a spike in blood corticosterone in mice, which is causal for NHO development.
BMC Musculoskeletal Disorders, 2024 • December 2, 2024
This case report details a 76-year-old male with DISH and OPLL who developed cervical spinal cord injury following osteophyte excision for respiratory distress and dysphagia. The patient's condition w...
KEY FINDING: Osteophyte excision in patients with cervical OPLL and spinal cord compression may lead to spinal cord injury due to increased intervertebral mobility.
Journal of Orthopaedic Surgery and Research, 2025 • December 25, 2024
This review summarizes recent findings regarding bone loss after SCI, changes in osteokines, and the effect of rehabilitation therapies, with a particular emphasis on the local and systemic regulatory...
KEY FINDING: Osteoporosis is common after SCI, especially in the distal femur and proximal tibia, increasing fracture risk.
Cureus, 2024 • December 19, 2024
This prospective study analyzed surgical outcomes of spinal fractures in 25 AS patients, revealing that falls from height were the primary cause of injury, with the C7-T1 level being the most common f...
KEY FINDING: The predominant cause of spinal injury in AS patients was falling from a height (56%), and the most frequent fracture location was the C7-T1 level.
The Journal of Spinal Cord Medicine, 2021 • July 1, 2021
This case report describes the effect of ESWT on NHO in a person with SCI who had been previously treated with non-steroidal anti-inflammatory drugs (NSAIDs), bisphosphonates, and physical modalities....
KEY FINDING: ESWT treatment reduced the patient's pain from a VAS score of 7-8 to 3 after 7 weeks of treatment.
The Journal of Spinal Cord Medicine, 2022 • May 1, 2022
This case report describes the application of long-term RSWT in a patient with NHO secondary to SCI. The patient demonstrated improvement in pain, ROM, and a reduction in lesion size. RSWT may improve...
KEY FINDING: Long-term RSWT was associated with a gradual decrease in the size of the heterotopic ossification lesion.
The Journal of Spinal Cord Medicine, 2022 • March 1, 2022
This case report describes a patient with paraplegia following radiation-induced myelopathy who developed DVT in the left common iliac vein (CIV) due to compression by neurogenic heterotopic ossificat...
KEY FINDING: DVT in the left common iliac vein (CIV) was observed in a patient with paraplegia.
The Journal of Spinal Cord Medicine, 2022 • July 1, 2022
This study analyzed data from a trial comparing functional electrical stimulation-assisted cycling (FESC) and passive cycling (PC) in patients with acute spinal cord injury (SCI). The analysis focused...
KEY FINDING: A strong, significant correlation was found between mean weekly exercise frequency and quadriceps and hamstring volumes.