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  4. A Comprehensive Analysis of Surgical Outcomes for Spinal Fractures in Patients With Ankylosing Spondylitis: A 13-Year Prospective Study

A Comprehensive Analysis of Surgical Outcomes for Spinal Fractures in Patients With Ankylosing Spondylitis: A 13-Year Prospective Study

Cureus, 2024 · DOI: 10.7759/cureus.76036 · Published: December 19, 2024

NeurologySurgeryMusculoskeletal Medicine

Simple Explanation

Ankylosing spondylitis (AS) leads to increased spinal stiffness, raising the risk of spine fractures, even from minor injuries. The spine becomes brittle due to bone formation in ligaments and fusion of spinal joints. In advanced AS, ossification of paraspinal tissues and inflammatory osteitis make the spine fragile and prone to fractures. This study focuses on surgical outcomes after spine fracture fixations in AS patients. The study emphasizes the effectiveness of surgical interventions for treating spine fractures in AS patients, leading to improvements in both quality of life and neurological status.

Study Duration
13 Years
Participants
25 cases of spinal fractures diagnosed with AS
Evidence Level
Prospective interventional study

Key Findings

  • 1
    The predominant cause of spinal injury in AS patients was falling from a height (56%), and the most frequent fracture location was the C7-T1 level.
  • 2
    Following surgery, patients showed notable improvements in neck disability index (NDI) and visual analog scale (VAS) scores, indicating enhanced quality of life and reduced pain.
  • 3
    Neurological status improved post-surgery, with a significant number of patients progressing to Frankel D and Frankel E categories, demonstrating enhanced motor and sensory function.

Research Summary

This prospective study analyzed surgical outcomes of spinal fractures in 25 AS patients, revealing that falls from height were the primary cause of injury, with the C7-T1 level being the most common fracture site. Surgical intervention led to significant improvements in NDI and VAS scores, indicating enhanced quality of life and reduced pain. Neurological status also improved, with many patients progressing to higher Frankel grades. The study concludes that anterior surgical interventions are effective for treating spine fractures in AS patients, improving neurological status and quality of life, but careful surgical planning and postoperative care are essential due to potential complications.

Practical Implications

Surgical Planning

Careful preoperative planning is crucial due to the increased risk of complications such as wound infection, sepsis, and instrumentation failure.

Neurological Monitoring

Close postoperative neurological monitoring is essential to promptly address any potential complications and optimize patient outcomes.

Rehabilitation Strategies

Implement comprehensive rehabilitation programs to maximize functional recovery and improve long-term quality of life for AS patients undergoing spinal fracture surgery.

Study Limitations

  • 1
    Small sample size
  • 2
    Single-center study
  • 3
    Not specified

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