Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 251-260 of 278 results
Photoacoustics, 2022 • December 14, 2021
This study investigates the feasibility of using photoacoustic physicochemical spectrograms (PCSs) for bone health assessment, focusing on variations in bone mineral density (BMD), bone microarchitect...
KEY FINDING: PAPCA can effectively characterize both the microstructure and content of multi-biomarkers highly related to bone health.
Frontiers in Cellular Neuroscience, 2022 • February 9, 2022
This study investigated the impact of heterotopic ossification (HO) on functional recovery in individuals with spinal cord injury (SCI) within the first year after injury, comparing them to matched co...
KEY FINDING: Individuals with heterotopic ossification achieved around 40% less functional improvement over time compared to their matched counterparts.
Frontiers in Endocrinology, 2022 • June 30, 2022
This study investigates the role of CD137 in age-related bone loss and senile osteoporosis. Through bioinformatics analysis of gene expression datasets, CD137 was identified as a potential key gene in...
KEY FINDING: Aged mice (18-month-old) exhibited significant bone loss compared to young mice (6-month-old), along with a tenfold increase in adipose tissue in the bone marrow cavity.
Medicina, 2022 • April 27, 2022
This study evaluated the clinical outcomes of minimal-invasive percutaneous dorsal screw-rod system for thoracolumbar fracture stabilization, focusing on patient-reported outcome measures (PROMs) and ...
KEY FINDING: Minimal-invasive stabilization of thoracolumbar fractures utilizing a dorsal percutaneous approach resulted in significant PROM outcome improvements for up to 1 year of follow-up.
Biomedical Optics Express, 2022 • May 1, 2022
The study introduces a multi-wavelength photoacoustic time-frequency spectral analysis (MWPA-TFSA) method for simultaneous detection of changes in bone minerals, lipids, and bone marrow cluster size, ...
KEY FINDING: Osteoporotic bones exhibit a lower content ratio of hemoglobin (Hb) to lipid compared to normal bones, as indicated by the lower energy ratio of E760/E930 in MWPA measurements.
BMC Musculoskeletal Disorders, 2022 • September 6, 2022
The study evaluated cartilage measurements using T2 mapping and R2* sequences in monkeys with normal and reduced knee ROM to determine which sequence is better at detecting microstructural cartilage c...
KEY FINDING: MRI-R2* sequence is superior to T2 mapping in the detection of microstructural cartilage changes in knees with limited ROM.
BMC Musculoskeletal Disorders, 2023 • March 28, 2023
This study investigated the feasibility of minimally invasive plate osteosynthesis (MIPO) for treating distal humeral fractures, including both extra-articular and intra-articular types. The researche...
KEY FINDING: Reduction and plate fixation of all distal humeral fractures (8 cadaveric) with and without osteotomy was feasible.
Bioengineering, 2023 • March 7, 2023
The study established a metaphyseal femoral non-union model in osteoporotic rats by comparing a piezoelectric saw versus a manual Gigli wire saw for osteotomy creation. Osteoporotic phenotype was indu...
KEY FINDING: Ovariectomized rats showed a significant reduction in cancellous and total bone mineral density compared to control rats, confirming the development of osteoporosis.
Nature Communications, 2023 • April 14, 2023
The study reports on an ultra-rare, rapidly progressive form of heterotopic ossification (HO) leading to premature death due to extensive ossification of connective tissue. The unique phenotype is cau...
KEY FINDING: An inter-chromosomal insertional duplication disrupts a topologically associating domain, causing an ultra-rare progressive form of heterotopic ossification.
BMC Surgery, 2023 • June 3, 2023
This study aimed to investigate the risk factors for adjacent vertebral compression fractures (AVCF) after vertebroplasty and to establish a clinical prediction model. The study identified low bone ma...
KEY FINDING: Low bone mass density (BMD) is an independent risk factor for AVCF after vertebroplasty.