Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 31-40 of 136 results
Top Spinal Cord Inj Rehabil, 2023 • July 1, 2023
This pilot study investigated the impact of intravesical Lactobacillus rhamnosus GG (LGG) on the urobiome of adults with neurogenic lower urinary tract dysfunction (NLUTD) who use intermittent cathete...
KEY FINDING: The urobiomes were characterized by four dominant phyla (>1%): Bacteroidetes, Firmicutes, Proteobacteria, and Actinobacteria.
npj Biofilms and Microbiomes, 2023 • December 4, 2023
This study investigates the relationship between spinal cord injury (SCI), gut dysbiosis, and neurological recovery, focusing on the role of short-chain fatty acids (SCFAs). The research involved anal...
KEY FINDING: SCI patients exhibited a decrease in SCFA-producing genera, such as Faecalibacterium, Megamonas, and Agathobacter, compared to healthy controls.
J. Clin. Med., 2024 • March 7, 2024
This review synthesizes the functional implications of TAI delivered via a rectal catheter with a balloon for managing NBD. Understanding its mechanism of action can bolster its utilization in bowel m...
KEY FINDING: TAI with a rectal catheter and balloon improves bowel symptoms compared to conservative management, including improvements in the NBD Score, Cleveland Clinic Constipation Score, and St. Mark’s Fecal Incontinence Score.
GUT MICROBES, 2024 • January 19, 2024
This study investigates the gut microbiome of individuals with spinal cord injury (SCI) at different stages of rehabilitation, comparing them to healthy controls. The primary aim was to determine if t...
KEY FINDING: The gut microbiome composition is significantly affected by the time elapsed since the spinal cord injury.
Infection Prevention in Practice, 2024 • January 27, 2024
This case series investigates the use of faecal microbiota transplantation (FMT) for decolonizing multidrug-resistant (MDR) bacteria in seven spinal cord injury (SCI) patients. The study found that FM...
KEY FINDING: FMT was successful in decolonizing MDR bacteria in five out of seven spinal cord injury patients.
Frontiers in Neuroscience, 2024 • June 17, 2024
This study evaluated the effects of exoskeleton-assisted walking (EAW) on bowel function and intestinal flora structure in motor-complete paraplegia patients. The results suggest that EAW can improve ...
KEY FINDING: EAW training led to a decrease in the amount of glycerol enemas used in the EAW group after 8 weeks of training.
Spinal Cord, 2024 • July 16, 2024
This systematic review and meta-analysis investigated the extent of bowel dysfunction after SCI and its impact on QoL. The study analyzed data from 39 articles, incorporating both quantitative and qua...
KEY FINDING: Bowel dysfunction is highly prevalent among individuals with SCI, with 74.7% reporting problems.
Metabolic Brain Disease, 2025 • March 18, 2025
This study investigates the potential of sodium butyrate (NaB) to alleviate spinal cord injury (SCI) by inhibiting pyroptosis. It establishes that SCFAs levels, particularly butyric acid, are signific...
KEY FINDING: SCFAs levels, especially butyric acid, significantly decreased after SCI, indicating changes in gut flora metabolites.
Revista Cuidarte, 2024 • July 9, 2024
The study aimed to develop and validate an educational technology for nurses to use in the rehabilitation of Neurogenic Bowel in people with Spinal Cord Injury. The educational technology was construc...
KEY FINDING: The integrative literature review proved necessary for the construction of the proposed educational technology and covered characteristics of the Neurogenic Bowel, bowel emptying techniques, guidelines and the systematization of nursing care.
The Journal of Spinal Cord Medicine, 2021 • July 1, 2021
This systematic review evaluates the evidence for digital rectal stimulation (DRS) as an intervention for managing upper motor neuron neurogenic bowel (UMN-NB) in adults with spinal cord injury (SCI)....
KEY FINDING: There is moderate evidence supporting the use of DRS in persons with SCI and UMN-NB.