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  4. Neurogenic Bowel Dysfunction in Patients with Spinal Cord Injury and Multiple Sclerosis—An Updated and Simplified Treatment Algorithm

Neurogenic Bowel Dysfunction in Patients with Spinal Cord Injury and Multiple Sclerosis—An Updated and Simplified Treatment Algorithm

J. Clin. Med., 2023 · DOI: 10.3390/jcm12226971 · Published: November 7, 2023

Spinal Cord InjuryNeurologyGastroenterology

Simple Explanation

Neurogenic bowel dysfunction (NBD) is a common condition in individuals with spinal cord injury (SCI) or multiple sclerosis (MS). It usually entails constipation, difficult evacuation of the rectum, and fecal incontinence (FI); often in combination. The current treatment algorithm, or treatment pyramid, does not completely correspond to actual clinical practice, and the known and classical pyramid contains both treatments still in their experimental stage as well as several treatments which are not available at all treatment centers. The authors of this paper therefore propose a simplified version of the treatment pyramid, aiming to guide clinicians in treating NBD.

Study Duration
Not specified
Participants
Patients with spinal cord injury (SCI) or multiple sclerosis (MS)
Evidence Level
Review

Key Findings

  • 1
    The existing treatment pyramid includes experimental treatments and treatments not available at all centers, making it misaligned with clinical practice.
  • 2
    The proposed simplified treatment algorithm focuses on commonly available treatments, starting with standard bowel management, followed by transanal irrigation (TAI), and surgery as the last stage.
  • 3
    Individual and continuous assessment is essential for determining when to advance in the treatment pyramid, adding or changing treatment based on patient preference and local clinical resources.

Research Summary

Neurogenic bowel dysfunction is a complex and common condition among patients with SCI and MS. It is highly burdensome due to constipation, fecal incontinence, abdominal bloating, and pain. The aim of the present paper is to shed light on the challenges of NBD and the current strategy of treatment and ultimately to present an updated, simplified treatment algorithm more coherent with current clinical practice. We therefore present an updated version of the treatment pyramid (Figure 2), aiming to facilitate an approach towards NBD treatment and guide most clinicians.

Practical Implications

Improved Treatment Algorithm

The simplified algorithm aids clinicians in navigating NBD treatment by focusing on commonly available and practical steps.

Individualized Patient Care

Emphasizes the importance of tailoring treatment to each patient's specific needs and preferences.

Guidance for Clinical Practice

Offers a more coherent and accessible approach to managing NBD in SCI and MS patients.

Study Limitations

  • 1
    Structured research and evidence regarding NBD treatment are very limited.
  • 2
    Research regarding NBD within patients with MS is likewise scant.
  • 3
    Various laxatives are yet to be compared in RCTs within the NBD population

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