Endocrinology Research

KEY FINDING: The probability of developing NAFLD increases as BMI increases in both SCI and Non-SCI cohorts.

KEY FINDING: SCI involves both primary injury, which is often irreversible, and secondary injury, which can be delayed and potentially treatable. Understanding the pathophysiology of secondary damage is crucial for timely specialist intervention.

KEY FINDING: The study found that 46.1% of the subjects had overt sarcopenia, and 10.1% had severe sarcopenia. Patients with severe sarcopenia had significantly lower BMI and MNA values.

KEY FINDING: Dysregulation of bone remodeling impairs immune cell function, leading to immune evasion and promoting tumor cell survival and growth in the bone.

KEY FINDING: Existing evidence suggested that NMES effectively improves glycemic control predominantly in middle-aged and elderly population with type 2 diabetes, obesity, and spinal cord injury.

KEY FINDING: Glucose levels were significantly higher in individuals with SCI compared to those without SCI at 60 and 120 minutes after an oral glucose tolerance test (OGTT).

KEY FINDING: Melatonin maintains the integrity of the blood–spinal cord barrier (BSCB), reducing edema and neutrophil infiltration after traumatic SCI.

KEY FINDING: Fasting insulin combined with the aspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio are appropriate predictors of sarcopenia.

KEY FINDING: Men with SCI had significantly lower bone mineral density in the hip region compared to community-dwelling men, but lumbar spine T-scores did not differ significantly.

KEY FINDING: Adults with TSCI and T2D had a higher incidence of all assessed morbidities compared to those with TSCI alone.