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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 61-70 of 339 results

Cardiovascular ScienceNeurologyGenetics

Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord

Basic Res Cardiol, 2024 • April 1, 2024

This study provides evidence suggesting that LPA contributes to myocardial I/R injury in mice by activating TRPV1-mediated signaling in the spinal cord. The study initially showed a strong association...

KEY FINDING: Myocardial I/R injury elevates CSF LPA levels, which is reduced by HA130 treatment.

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Spinal Cord InjuryCardiovascular ScienceDermatology

Effects of alternating pressure patterns on sacral skin blood flow responses in people with spinal cord injury

Int Wound J, 2024 • February 2, 2024

This study investigates the impact of varying pressure amplitudes and cycle-time periods of alternating pressure (AP) on sacral skin blood flow in individuals with spinal cord injury (SCI). The result...

KEY FINDING: During the high-pressure phase, there was a significant difference between the 75/5 and 65/15 mmHg protocols.

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Cardiovascular Science

Utilizing physician modified fenestration on the castor branched stent technique for reconstruction of an isolated left vertebral artery on the aortic arch

Scientific Reports, 2024 • February 16, 2024

This study investigates the use of physician-modified fenestration (PMF) on a Castor branched stent for isolated left vertebral artery (ILVA) reconstruction during thoracic endovascular aortic repair ...

KEY FINDING: The PMF on Castor branched stent technique achieved a 100% technical success rate in reconstructing the ILVA in all 25 patients.

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Cardiovascular ScienceBiomedical

Clinical comparative analysis of 3D printing‑assisted extracorporeal pre‑fenestration and Castor integrated branch stent techniques in treating type B aortic dissections with inadequate proximal landing zones

BMC Cardiovascular Disorders, 2024 • March 1, 2024

This study compared 3D printing-assisted extracorporeal pre-fenestration TEVAR and castor-integrated branch stent techniques for treating Stanford type B aortic dissection with inadequate proximal anc...

KEY FINDING: The surgical success rate and device deployment success rate were 100% in both groups.

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Spinal Cord InjuryCardiovascular ScienceSurgery

Predictive value of preoperative platelet count and D-dimer levels for spinal cord injury following acute type a aortic dissection

Journal of Cardiothoracic Surgery, 2024 • March 5, 2024

This study aims to identify the risk factors contributing to spinal cord injury (SCI) following a type A acute aortic dissection (TA-AAD). The resulting data of the multivariate logistic regression an...

KEY FINDING: Preoperative platelet count (odds ratio [OR] = 0.774) and D-dimer levels (OR = 2.247) could serve as independent predictors for postoperative SCI in patients with TA-AAD.

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Cardiovascular ScienceSurgerySpinal Disorders

Diagnostic, clinical management, and outcomes in patients with spinal dural arteriovenous fistula

Front. Surg., 2024 • March 5, 2024

This study retrospectively analyzed 81 patients with SDAVF treated surgically or endovascularly between 2002 and 2023, focusing on demographics, diagnostic history, treatment characteristics, and clin...

KEY FINDING: SDAVF occurs more frequently in men, typically in their 60s, and diagnosis is often delayed, averaging about 12 months from the onset of symptoms.

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Cardiovascular ScienceNeurologyResearch Methodology & Design

Radiation induced delayed transverse myelitis and neurological deficit at tertiary care center

Annals of Medicine and Surgery, 2021 • January 1, 2021

This case report describes a 43-year-old male with CML who developed transverse myelitis following radiation therapy. The patient presented with a complex array of symptoms, including back pain, neuro...

KEY FINDING: The patient developed transverse myelitis after radiation therapy for CML, presenting with back pain, numbness, and loss of sphincter tone.

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Spinal Cord InjuryCardiovascular ScienceAnesthesiology

Delayed Paraparesis: An Unusual Complication Following Coarctation of Aorta Repair

Annals of Cardiac Anaesthesia, 2024 • January 12, 2024

This case report describes a rare instance of delayed paraparesis following coarctation of the aorta (CoA) repair, highlighting the potential for spinal cord injury (SCI) even in relatively straightfo...

KEY FINDING: The patient developed bilateral lower limb weakness on postoperative day 5, with MRI showing signs of ischemic insult to the cauda equina nerve roots.

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Cardiovascular ScienceSurgery

The Fate of Conventional Elephant Trunk in the Frozen Elephant Trunk Era

Aorta, 2023 • May 16, 2024

Conventional elephant trunk (cET) and frozen elephant trunk (FET) are two distinct approaches to the surgical treatment of thoracic aortic aneurysms and dissections. FET remains limited by spinal cord...

KEY FINDING: FET is advantageous when pathology is confined to the proximal descending aorta, showing similar operative outcomes to cET but without needing a second-stage procedure and better false lumen remodeling.

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Cardiovascular ScienceSurgery

Two-stage hybrid surgical repair for aortic arch pathology with a shaggy aorta: a case report

Journal of Cardiothoracic Surgery, 2024 • June 14, 2024

The surgical treatment strategy for aortic arch pathology with a shaggy aorta must be determined on a case-by-case basis because of the risk of catastrophic complications, such as brain infarction and...

KEY FINDING: Total arch replacement with the conventional elephant trunk and secondary thoracic endovascular aortic repair may be an effective alternative for aortic arch pathology with a shaggy aorta.

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