Cardiovascular Science Research

KEY FINDING: A subset of pericytes (Glast+) contributes significantly to fibrotic scar formation after spinal cord injury in mice.

KEY FINDING: The study evaluates the effects and durability of a structured, multi-modal intervention on health and function for SCI patients and their caregivers.

KEY FINDING: BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance.

KEY FINDING: Para table tennis training significantly reduced the physical stress index (PSI) in participants with SCI.

KEY FINDING: Neurotrophic factors like diencephalon astrocyte derived neurotrophic factor and cerebrolysin can reduce abnormal permeability of the blood-spinal cord barrier and improve functional recovery.

KEY FINDING: Age increased odds for CMD diagnosis by 1.05 per year (P = 0.02) and was directly related to elevated body mass index (BMI, β = 0.42, P < 0.05), fasting glucose (β = 0.58, P < 0.01), and higher systolic blood pressure (β = 0.31, P < 0.10).

KEY FINDING: Time since injury was significantly associated with a continuous decline in cardiac structure and systolic function, specifically, a reduction in left ventricular mass, internal diameter during systole and diastole, as well as cardiac output, and left ventricular percent shortening.

KEY FINDING: Ligation of intercostal arteries induced a significant and instantaneous drop in blood flow in both the intercostal arteries and the thoracic spinal cord.

KEY FINDING: Midodrine significantly increased average 30-day systolic and diastolic blood pressure compared to placebo.

KEY FINDING: The patient was diagnosed with inferior STEMI combined with hyperextension cervical spine injury, a rare and challenging clinical presentation.