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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 51-60 of 339 results

Spinal Cord InjuryCardiovascular SciencePharmacology

Recombinant Neorudin for the Prevention of Deep-Vein Thrombosis After Spinal-Cord Injury

Drug Design, Development and Therapy, 2023 • August 23, 2023

EH inhibited thrombosis after SCI in a dose-dependent manner. Application of EH did not increase bleeding in the injured SC or damage nerve function. EH may provide a safe and effective anticoagulant ...

KEY FINDING: EH inhibited thrombosis in a dose-dependent manner by reducing the wet weight and dry weight of the thrombus.

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Spinal Cord InjuryCardiovascular ScienceOrthopedics

Incidence of vertebral artery injury in patients undergoing cervical spine trauma surgery in correlation with surgical approach: A review

Medicine, 2023 • September 15, 2023

This review investigates the incidence of iatrogenic vertebral artery injury during cervical spine surgery, focusing on the correlation with surgical approach (anterior vs. posterior). The analysis of...

KEY FINDING: The anterior surgical approach to the cervical spine is generally associated with a lower risk of vertebral artery injury (0.3–0.5%) compared to the posterior approach (4.1% to 8.2%).

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Spinal Cord InjuryCardiovascular ScienceSurgery

False lumen–dependent segmental arteries are associated with spinal cord injury in frozen elephant trunk procedure for acute type I aortic dissection

JTCVS Open, 2023 • September 1, 2023

This study aimed to investigate the association between false lumen (FL) dependency of segmental arteries (SAs) at T9-L3 levels and the risk of spinal cord injury (SCI) following total arch replacemen...

KEY FINDING: FL dependency of SAs at the T9-L3 levels was significantly associated with the development of SCI following FET implantation in AAD.

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Cardiovascular ScienceRheumatologyNeurology

Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review

Frontiers in Neurology, 2023 • September 22, 2023

This case report presents a rare instance of acute spinal cord infarction (SCI) in a patient with ankylosing spondylitis (AS). The patient presented with sudden lower limb weakness and was diagnosed w...

KEY FINDING: A 54-year-old man with a history of ankylosing spondylitis, scoliosis, and hypotension presented with acute spinal cord infarction.

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Spinal Cord InjuryCardiovascular ScienceSurgery

Impact of preoperative identification of the artery of Adamkiewicz on spinal cord injury after descending aortic and thoracoabdominal aortic repair

Ann Cardiothorac Surg, 2023 • August 10, 2023

This study aimed to evaluate the impact of preoperative AKA identification on reducing SCI incidence in OR and EVR for dTA and TAA pathologies. The study found that preoperative identification of the ...

KEY FINDING: Preoperative identification of the AKA was useful enough to determine treatment strategies with less likelihood of SCI in both OR and EVR for dTA and TAA pathologies.

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Spinal Cord InjuryCardiovascular ScienceMedical Imaging

Near-Infrared Spectroscopy for Spinal Cord Monitoring—A Roadmap to Translational Research in Aortic Medicine

Aorta, 2023 • November 10, 2023

The article reviews translational research on using collateral network near-infrared spectroscopy (cnNIRS) for spinal cord monitoring during aortic repair. Studies in animal models and clinical settin...

KEY FINDING: Lumbar cnNIRS reproducibly reflects spinal cord tissue oxygenation and perfusion in real time and appears a feasible method for clinical practice.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Protective effect of valproic acid on ischemia-reperfusion induced spinal cord injury in a rat model

The Journal of Spinal Cord Medicine, 2024 • May 1, 2024

The main focus of the study research was the potential role of VPA in aortic surgeries. The research elucidated VPA’s anti-inflammatory, anti-oxidant, and anti-apoptotic attributes in the spinal cord ...

KEY FINDING: VPA administration before or after ischemia-reperfusion reduced IL-18 level but not to pre-ischemic levels.

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Cardiovascular ScienceOrthopedicsMusculoskeletal Medicine

Coagulation parameters correlate to venous thromboembolism occurrence during the perioperative period in patients with spinal fractures

Journal of Orthopaedic Surgery and Research, 2023 • November 25, 2023

This retrospective study investigated the correlation between coagulation parameters and VTE occurrence in patients with spinal fractures. It identified several risk factors, including age, spinal cor...

KEY FINDING: D-Dimer, FIB, and FDP levels were significantly elevated in VTE patients compared to non-VTE patients.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Autonomic Dysreflexia in Spinal Cord Injury: Mechanisms and Prospective Therapeutic Targets

Neuroscientist, 2024 • October 1, 2024

Autonomic dysreflexia, a common complication of high-level SCI, is characterized by sudden hypertension and bradycardia due to unregulated sympathetic reflexes. The mechanisms involve loss of supraspi...

KEY FINDING: Transplantation of embryonic presympathetic neurons into the injured spinal cord can reestablish supraspinal regulation of sympathetic activity, reducing autonomic dysreflexia in rodent SCI models.

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Cardiovascular ScienceSurgery

Frozen elephant trunk in acute aortic dissection: a literature review

Indian Journal of Thoracic and Cardiovascular Surgery, 2023 • November 13, 2023

Acute aortic dissection is a complex and life-threatening cardiovascular disorder, requiring urgent surgical treatment. The frozen elephant trunk (FET) technique has emerged as a valuable strategy for...

KEY FINDING: FET is a commonly used treatment approach for acute type A aortic dissection.

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