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  4. Utilizing physician modified fenestration on the castor branched stent technique for reconstruction of an isolated left vertebral artery on the aortic arch

Utilizing physician modified fenestration on the castor branched stent technique for reconstruction of an isolated left vertebral artery on the aortic arch

Scientific Reports, 2024 · DOI: 10.1038/s41598-024-54781-8 · Published: February 16, 2024

Cardiovascular Science

Simple Explanation

The study explores a method to protect the isolated left vertebral artery (ILVA) during thoracic endovascular aortic repair (TEVAR). This is achieved using a physician-modified fenestration (PMF) on a single-branched stent, called Castor. The Castor stent with PMF is placed in the aortic arch to maintain blood flow to the ILVA during the TEVAR procedure. This approach aims to prevent complications like posterior cerebral ischemia or spinal cord ischemia. Preliminary findings suggest this technique is practical, safe, and effective for preserving the ILVA during TEVAR under local anesthesia. The study followed patients for an average of 28.5 months.

Study Duration
June 2018 to December 2022
Participants
25 patients with ILVA undergoing TEVAR
Evidence Level
Retrospective, multi-centre study

Key Findings

  • 1
    The PMF on Castor branched stent technique achieved a 100% technical success rate in reconstructing the ILVA in all 25 patients.
  • 2
    The procedure effectively maintained ILVA patency for all patients during the follow-up period, with a low rate of reintervention for endoleak.
  • 3
    No aortic rupture, stroke, or spinal cord injury occurred throughout the follow-up period after discharge, suggesting the safety of the technique.

Research Summary

This study investigates the use of physician-modified fenestration (PMF) on a Castor branched stent for isolated left vertebral artery (ILVA) reconstruction during thoracic endovascular aortic repair (TEVAR). The study included 25 patients who underwent this procedure between June 2018 and December 2022. The results showed a 100% technical success rate, with effective maintenance of ILVA patency during follow-up. The technique also demonstrated a low incidence of major adverse events, such as aortic rupture or spinal cord injury. The authors conclude that PMF on a Castor branched stent is a feasible, safe, and effective approach for ILVA reconstruction during TEVAR, particularly when performed under local anesthesia.

Practical Implications

Clinical Practice

The PMF on Castor branched stent technique can be considered as a viable option for ILVA reconstruction during TEVAR, especially in patients with anatomical challenges or when local anesthesia is preferred.

Future Research

Further studies with larger cohorts and longer follow-up periods are warranted to validate the long-term efficacy and durability of this technique.

Technological Development

This study supports the continued refinement of stent graft technology and PMF techniques to improve outcomes in complex aortic arch reconstructions.

Study Limitations

  • 1
    Small population size due to the low incidence of ILVA.
  • 2
    Potential impact of the surgeon’s experience on the surgery results.
  • 3
    Restrictions on data availability.

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