Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 221-230 of 904 results
Int. J. Mol. Sci., 2022 • September 29, 2022
This work introduces a cost-efficient gelatin-based submicron patterned hydrogel–fiber composite with tuned stiffness, able to support cell attachment, differentiation and alignment of neurons derived f...
KEY FINDING: Fiber–hydrogel composites with a modulus of about 20 kPa showed the strongest cell attachment and highest cell proliferation, rendering them an ideal differentiation support.
Sensors, 2022 • February 25, 2022
This study developed a coaching system for FES-rowing to improve the timing of stimulation for individuals, particularly those with spinal cord injuries. The system provides real-time audiovisual feed...
KEY FINDING: Vastus lateralis (VL) activation begins consistently before the seat reaches the anterior-most position during rowing.
Frontiers in Medical Technology, 2022 • February 22, 2022
This review explores the emerging field of neural stem cell therapy and the engineering of functionalized biomaterials to facilitate cell transplantation and promote regeneration of damaged spinal cor...
KEY FINDING: NSCs are multipotent cells that can self-renew and generate all the specialized neural cells within the spinal cord, that is, neurons, astrocytes and oligodendrocytes.
IEEE Trans Control Syst Technol, 2021 • September 1, 2021
This paper introduces a tube-based model predictive control (MPC) method for a hybrid neuroprosthesis, combining functional electrical stimulation (FES) and an electric motor to regulate knee joint mo...
KEY FINDING: The tube-based MPC method was proven to have recursive feasibility, compliance to input constraints, and exponentially bounded stability, suggesting its suitability for real-time control applications.
Journal of Tissue Engineering, 2022 • February 23, 2022
This study investigates the potential of self-assembling peptide gels, specifically RADA16 modified with substance P, to promote angiogenesis and functional recovery after spinal cord injury (SCI) in ...
KEY FINDING: The inflammatory cell population in the lesion cavity was decreased in rats that received RADA16 with substance P.
Journal of NeuroEngineering and Rehabilitation, 2022 • April 5, 2022
The study introduces an algorithm (OIDA) for automated determination of stimulation patterns in FES-Cycling, utilizing torque feedback to identify optimal stimulation intervals for specific muscle gro...
KEY FINDING: The OIDA algorithm successfully identified stimulation intervals for the left and right quadriceps and hamstring muscles in a subject with complete SCI.
Journal of NeuroEngineering and Rehabilitation, 2022 • March 28, 2022
The study presents enhancements to an FES cycling system using a User-centered design approach, including an improved user interface and spatially distributed sequential stimulation (SDSS). User evalu...
KEY FINDING: User perception measured with SUS indicates a positive outcome in the developed system, with a total SUS score of 77.5.
Sensors, 2022 • May 7, 2022
This paper introduces a 4-channel open-access IoT electrostimulator designed for motor rehabilitation, particularly for individuals with spinal cord injuries. It emphasizes the limitations of existing...
KEY FINDING: The designed hardware allows free adjustment of boost converter voltage and signal modulation with 200 µs pulse duration and 50 Hz frequency.
Journal of NeuroEngineering and Rehabilitation, 2022 • May 13, 2022
This study presents a modular BCI system designed for at-home use, featuring a user-friendly mobile interface and plug-and-play compatibility with multiple end effectors. The system was tested on a su...
KEY FINDING: Bluetooth data transmission delay between the minicomputer and mobile app averaged 23 ms.
Journal of Nanobiotechnology, 2022 • June 4, 2022
The study introduces a novel biomimetic synthesis method for ultrasmall Pd nanoclusters (Pd@insulin) using insulin as a template, demonstrating its effectiveness in scavenging ROS and improving outcom...
KEY FINDING: Insulin-incubated palladium clusters (Pd@insulin) were successfully synthesized using a green biomimetic method and exhibited excellent multiple ROS-scavenging ability.