Biomedical Research

KEY FINDING: Fat tissue in the buttock could reduce the contact pressure when sitting on the rigid seat.

KEY FINDING: Participants with a history of PrIs had significantly darker adipose under the ischium than surrounding the ischium compared to participants without a history of PrIs.

KEY FINDING: The developed system allows for simultaneous recording of neural and muscular activity from multiple sites in the motor pathway of freely moving rats.

KEY FINDING: The white matter-like tissue (WMLT) transplantation group showed significant improvement in coordinated motor functions compared with the control groups.

KEY FINDING: The developed high-power FES device can generate biphasic electrical pulses with amplitude, width, and frequency up to 150 mA, 1000 µs, and 100 Hz, respectively.

KEY FINDING: The LCP-based spinal cord stimulator effectively suppressed pain in a rat model of spared nerve injury.

KEY FINDING: The controllers developed in this study achieved repeatable and consistent kinematic joint trajectories as a function of the gait cycle.

KEY FINDING: Biomaterials can be engineered to mimic the extracellular matrix of nerve tissue, providing a scaffold for axonal regeneration and facilitating the delivery of therapeutic agents to the injury site.

KEY FINDING: The BIOTILC controller effectively learned to achieve the desired leg swing motion, balancing muscular and motor contributions to minimize error.

KEY FINDING: Wheelchair users turn approximately 900 times per day, indicating that changing direction is a fundamental aspect of wheelchair use.