Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 901-904 of 904 results
Wiley Interdiscip Rev Nanomed Nanobiotechnol, 2010 • March 1, 2010
The review discusses the challenges of nerve injuries and the limitations of axon regeneration in the central nervous system (CNS) and peripheral nervous system (PNS). It explores two main strategies ...
KEY FINDING: Nanomaterials can support axon regeneration by providing artificial constructs that replace the inhibitory environment in the CNS and PNS.
TISSUE ENGINEERING: Part A, 2010 • October 1, 2010
This study investigates the effect of astrocyte alignment on neuronal growth using a 3D collagen gel culture system, finding that aligned astrocytes enhance neurite outgrowth. The researchers develope...
KEY FINDING: Astrocyte alignment is significantly greater at the edge and middle of tethered rectangular collagen gels compared to unaligned delta zones.
J Neurosci Res, 2010 • November 1, 2010
This study demonstrates that injection of IKVAV-PA into the injured spinal cord consistently improves behavioral outcome in both rats and mice with different spinal cord injury models. The major poten...
KEY FINDING: IKVAV PA injection leads to a significantly higher density of serotonergic fibers caudal to the injury site in the chronically injured spinal cord.
Tissue Engineering: Part A, 2011 • February 2, 2011
The study introduces a method for sustained drug delivery to the transected spinal cord using PLGA microspheres within OPF hydrogels. In vitro and in vivo experiments demonstrated the biological activ...
KEY FINDING: Encapsulating dbcAMP in microspheres prolonged its release and maintained its functionality.