Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 81-90 of 12,052 results
Front. Rehabil. Sci., 2025 • February 26, 2025
This pilot study examined the safety, feasibility, and effects on spasticity and muscle atrophy of an early rehabilitation technique using non-invasive sensory stimulation and called functional propri...
KEY FINDING: Early FPS is feasible and safe for SCI patients as early as the intensive care unit stage.
Inflammopharmacology, 2025 • February 26, 2025
The study investigated the therapeutic efficacy of certolizumab, a TNF-α inhibitor, in a rat model of spinal cord injury (SCI). Results showed that certolizumab treatment reduced neuroinflammation, su...
KEY FINDING: Certolizumab downregulated the expression of TNF-α, NF-κB, and IL-6, key inflammatory mediators.
IBRO Neuroscience Reports, 2025 • February 25, 2025
This study explores the potential synergistic effects of combining oscillating field stimulation (OFS) with Atorvastatin (ATR) in treating spinal cord injury (SCI) in rats. SCI was induced at the T9 s...
KEY FINDING: The combination of Atorvastatin with OFS stimulation promotes neural recovery after SCI, highlighting the potential of combination therapies in enhancing regenerative outcomes.
Frontiers in Neuroscience, 2025 • February 25, 2025
This study analyzed research trends on cognitive dysfunction after traumatic brain injury (TBI) from 2004 to 2023 using bibliometric methods. The analysis identified key journals, institutions, countr...
KEY FINDING: The Journal of Neurotrauma is the most productive and influential journal in this field.
Journal of Rehabilitation Medicine, 2025 • February 25, 2025
This study is the first in Malaysia to successfully employ a path analysis model in investigating HCU and HCSS among individuals with SCI. First, the HCU was predicted by health problems, which in tur...
KEY FINDING: Health problems predicted healthcare utilization, while activity limitation and participation restriction predicted healthcare services satisfaction.
bioRxiv, 2025 • February 25, 2025
This study challenges the traditional understanding of noradrenergic modulation of spinal nociceptive transmission by demonstrating that targeted blockade of spinal α2 receptors can promote anti-nocic...
KEY FINDING: Targeted blockade of spinal α2 adrenoceptors can reduce spinal nociceptive transmission in vivo.
eLife, 2024 • February 24, 2025
This study developed an in vitro model of DRG neurons that recapitulates their in vivo development, pseudo-unipolarization, and establishment of polarity, serving as a valuable resource for understand...
KEY FINDING: DRG neurons in vitro undergo pseudo-unipolarization, replicating in vivo asymmetries and regenerative capacity.
JMIR Formative Research, 2025 • February 24, 2025
This study evaluated the effectiveness of financial support workshops for patients with DCM under state pension age in the UK. The workshops, focusing on UC and PIP, were delivered in partnership with...
KEY FINDING: Participants rated the usefulness of the UC and PIP sessions highly, with average ratings of 9.00/10 and 10/10, respectively.
Cureus, 2025 • February 23, 2025
This case report highlights the severe consequences of a preventable burn injury in a patient with paraparesis due to spinal cord injury, ultimately leading to amputation. The importance of early inte...
KEY FINDING: A preventable burn injury, compounded by impaired sensation and delayed recognition, led to complications that eventually necessitated a below-knee amputation.
Cureus, 2025 • February 22, 2025
This case report discusses the effective use of spinal cord stimulation (SCS) to treat lower limb pain caused by conus medullaris syndrome. This case highlights the diagnostic difficulties associated ...
KEY FINDING: The patient experienced electric shock-like pain during epidural anesthesia for laparoscopic colon resection, which persisted postoperatively, leading to the diagnosis of conus medullaris syndrome.