Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 41-50 of 12,052 results
Front. Cell Dev. Biol., 2025 • March 12, 2025
This study investigates the potential of cerebrospinal fluid-contacting neurons (CSF-cNs) as adult neural stem cells for transplantation therapy in spinal cord injury (SCI), focusing on their self-ren...
KEY FINDING: CSF-cNs, isolated using a Pkd2l1 promoter-driven GFP reporter, exhibit excellent self-renewal capability in vitro.
CNS Neuroscience & Therapeutics, 2025 • March 11, 2025
This study investigates the role of ferritinophagy-mediated ferroptosis in spinal cord ischemia-reperfusion injury (SCIRI) and the potential therapeutic effects of hydrogen sulfide (H2S). The results ...
KEY FINDING: SCIRI induces autophagic ferritin degradation, leading to iron-dependent ferroptosis.
Journal of Rehabilitation and Assistive Technologies Engineering, 2025 • March 10, 2025
The study evaluated the Advanced MLRGO's performance against Prime-Walk and standard MLRGO models, focusing on walking speed, travel distance, and donning/doffing times in individuals with thoracic SC...
KEY FINDING: The Advanced MLRGO significantly improved walking speed compared to the standard MLRGO (p = 0.033), indicating a 50.7% increase.
J Neurosurg Case Lessons, 2025 • March 10, 2025
This case report presents a 17-year-old female with spinal osteosarcoma who achieved 20-year disease-free survival following neoadjuvant chemotherapy and en bloc resection, including spinal cord amput...
KEY FINDING: En bloc resection with tumor-free margins, including the spinal cord, can lead to long-term disease-free survival in spinal osteosarcoma, challenging the notion that spinal OS has a universally poor prognosis.
Cureus, 2025 • March 9, 2025
This case report describes a 72-year-old male who developed white cord syndrome (WCS) after undergoing posterior cervical laminectomy and fusion for cervical stenosis due to ossification of the poster...
KEY FINDING: The patient developed WCS after posterior cervical decompression and fusion for cervical stenosis caused by ossification of the posterior longitudinal ligament (OPLL).
J. Clin. Med., 2025 • March 8, 2025
This randomized clinical trial protocol outlines a study to determine the effects of exoskeleton-assisted walking (EAW) combined with epidural stimulation (ES) and resistance training (RT) on volition...
KEY FINDING: The restoration of locomotion with ES and EAW may result in a reduction in psychosocial, cardiovascular, and metabolic bladder parameters and socioeconomic burden.
International Journal of Nanomedicine, 2025 • March 8, 2025
The study successfully constructed a hydrogel-loaded lyophilized hucMSCs-exo drug delivery system, which is called exo@H, and demonstrated its effectiveness in treating periodontitis in mice. Exo@H pr...
KEY FINDING: Lyophilized hucMSCs-exo promoted the proliferation and osteogenic differentiation of MC3T3-E1 cells, and showed more significant abilities in combination with hydrogel.
Journal of Neurology, 2025 • March 7, 2025
This systematic review examined the effects of music and dance-based rehabilitation on neuroplasticity in individuals with neurological disorders, focusing on studies that used neuroimaging techniques...
KEY FINDING: Dance-based interventions can help prevent brain shrinkage in areas important for memory, especially in people at risk of dementia.
Journal of Pain Research, 2025 • March 7, 2025
This study investigates the therapeutic effects of electroacupuncture (EA) on neuropathic pain (NP) in a rat model. The research focuses on the role of NLRP3 inflammasome-mediated pyroptosis in microg...
KEY FINDING: EA treatment significantly alleviated pain hypersensitivity by increasing the MWT and PWL in CCI rats.
Bioelectronic Medicine, 2025 • March 6, 2025
The study investigated the effects of low-intensity trans-spinal focused ultrasound (tsFUS) on neuropathic pain in rats with chronic constriction injury (CCI). tsFUS was applied to the L5 spinal segme...
KEY FINDING: tsFUS treatment increased the von Frey threshold (vFT) in rats with CCI compared to sham treatment, indicating reduced mechanical sensitivity. This effect persisted for up to 23 days post-CCI.