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  4. White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion

White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion

Cureus, 2025 · DOI: 10.7759/cureus.80295 · Published: March 9, 2025

SurgerySpinal Disorders

Simple Explanation

White cord syndrome (WCS) is a rare but serious complication that can occur after spinal decompression surgery. It may be related to reperfusion injury, where blood flow returns to the spinal cord after a period of compression. The patient experienced quadriparesis (weakness in all four limbs) following surgery, and postoperative imaging showed spinal cord edema, which is consistent with WCS. The patient later developed respiratory distress, hemodynamic instability and infection. This case underscores the importance of assessing individual risk factors before surgery, closely monitoring neurological function during surgery, and promptly addressing any signs of WCS if it is suspected.

Study Duration
Not specified
Participants
72-year-old Hispanic male
Evidence Level
Case Report

Key Findings

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    The patient developed WCS after posterior cervical decompression and fusion for cervical stenosis caused by ossification of the posterior longitudinal ligament (OPLL).
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    Intraoperative neuromonitoring signals decreased significantly after laminectomy, indicating potential spinal cord injury.
  • 3
    Postoperative MRI revealed spinal cord edema and T2 hyperintensities, consistent with WCS, despite adequate decompression.

Research Summary

This case report describes a 72-year-old male who developed white cord syndrome (WCS) after undergoing posterior cervical laminectomy and fusion for cervical stenosis due to ossification of the posterior longitudinal ligament (OPLL). The patient experienced significant quadriparesis and postoperative imaging revealed spinal cord edema and T2 hyperintensities consistent with WCS. Despite interventions, the patient's condition deteriorated, leading to death. The report highlights the importance of risk factor assessment, neuromonitoring, and prompt treatment for suspected WCS to improve patient outcomes.

Practical Implications

Risk Stratification

Careful assessment of patient risk factors, such as advanced age and OPLL, is crucial before spinal decompression surgery.

Neuromonitoring Importance

Intraoperative neuromonitoring is essential for early detection of spinal cord injury during surgery.

Prompt Intervention

Early intervention with measures such as increasing MAP and administering steroids may be beneficial in managing suspected WCS.

Study Limitations

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