Long-Term Outcomes of Nano-Hydroxyapatite/Polyamide 66 Strut in Thoracolumbar Burst Fractures

Med Sci Monit, 2024 · DOI: 10.12659/MSM.946091 · Published: December 24, 2024

Simple Explanation

High-energy injuries, like car accidents, can cause thoracolumbar burst fractures, leading to spinal instability and cord compression. Anterior decompression with stabilization provides strong support, kyphosis correction, and bone fusion. This study evaluated long-term outcomes of using a nano-hydroxyapatite/polyamide 66 strut in 38 thoracolumbar fracture cases.

Study Duration

12.50±1.19 years

Participants

38 patients with thoracolumbar burst fractures

Evidence Level

Not specified

Key Findings

1
At the final FU, the patients of ASIA B, C, and D recovered to E.
2
All patients fused with a mean of 4.10±1.21months.
3
Cobb angle and percentage of vertebral body height loss of preoperation had a significant difference between before surgery, at 1-year FU, and at final FU (P<0.05).

Research Summary

Long-term results of clinical and radiographic assessment of the n-HA/PA66 strut in treating thoracolumbar burst fractures could achieve satisfactory solid anterior support, effective restoration of intervertebral height, and good maintenance of thoracolumbar alignment. The anterior approach was associated with fewer complications than the posterior approach. In long-term FU, our study observed satisfactory improvement in the VAS score and ODI at the final FU.

Practical Implications

Effective Spinal Support

The n-HA/PA66 strut provides satisfactory solid anterior support for thoracolumbar burst fractures.

Restoration of Intervertebral Height

The strut effectively restores intervertebral height, improving spinal alignment.

Maintenance of Alignment

The n-HA/PA66 strut helps maintain good thoracolumbar alignment in the long term.

Study Limitations

1
Its retrospective nature may have caused bias.
2
47.35% of the patients lost the contact information.
3
There may have been bias due to lack of a control group and there may be related with bias.

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