Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 251-260 of 12,052 results
BMJ Case Rep, 2025 • January 10, 2025
Cervical fracture dislocation often leads to neurological deficits, manifesting with sensory and motor symptoms, which may persist even after surgical intervention. In Case 1, the patient presented wi...
KEY FINDING: Case 1 involved a patient with left-hand numbness after a car accident who had a C5/C6 facet fracture dislocation and spinal cord indentation, treated with open reduction and fixation.
Biomedicines, 2025 • January 10, 2025
This study investigated the effectiveness of epidural electrical stimulation (EES) in improving sensory recovery and walking function in three patients with chronic incomplete spinal cord injury (SCI)...
KEY FINDING: Participants receiving EES significantly increased the muscle activity in most lower limb muscles.
Advanced Science, 2025 • January 9, 2025
The study introduces a SETLSA strategy for spinal cord injury (SCI) treatment based on cerium (Ce)-doped upconversion antioxidant nanoenzymes (Ce@UCNP-BCH). These nanoenzymes eliminate reactive oxygen...
KEY FINDING: Ce@UCNP-BCH effectively facilitates the regeneration of spinal cord including myelin sheath, and promotes the functional recovery of SCI mice.
Scientific Reports, 2025 • January 9, 2025
The study aimed to analyze cervical sagittal alignment changes following growing rod treatment in early-onset scoliosis (EOS) and identify risk factors for cervical imbalance using machine learning. T...
KEY FINDING: Growing rod surgery significantly affects cervical sagittal alignment in EOS patients.
J. Clin. Med., 2025 • January 9, 2025
Posterior vertebral resection techniques offer significant promise in the correction of pediatric spinal deformities. Careful case-by-case evaluation is necessary, especially because of the associated...
KEY FINDING: PVCR resulted in an average reduction in the Cobb angle from 86.3◦ preoperatively to 22.4◦ postoperatively, with a mean correction of 64%.
Communications Biology, 2025 • January 9, 2025
This study uses spatial transcriptomics (ST), single-nucleus RNA-sequencing (snRNA-seq) and bulk RNA-sequencing (bulk RNA-seq) to characterize regional pathological heterogeneity of the spinal cord (S...
KEY FINDING: The study found unique spatial atlases of genes, cell populations, cell-cell cross-talks, signaling pathways, and transcriptional regulatory networks in the spinal cord of neuropathic pain mice compared to sham mice.
Frontiers in Immunology, 2025 • January 9, 2025
This study explores the spatial dynamics of immune cells in spinal cord injury, highlighting their complex role in the recovery process. Immune cells not only contribute to healing and protecting the ...
KEY FINDING: The spatial dynamics of immune cells following SCI are crucial for understanding their mechanisms in neuroinflammation and repair, and for developing new therapies.
Spinal Cord, 2025 • January 9, 2025
This systematic scoping review examined the psychological outcomes of using extended reality (XR) interventions in spinal cord injury (SCI) rehabilitation. It included 13 studies, all of which used vi...
KEY FINDING: VR interventions can provide enjoyment, relaxation, and a source of positive distraction for individuals with SCI.
Cell Transplantation, 2025 • January 8, 2025
Cell transplantation is a promising therapeutic approach for rebuilding functional motor systems, particularly the CST, but there is still significant potential for improvement in optimizing its thera...
KEY FINDING: The glial scar has a duality: a regenerative surface and an anti-regenerative core.
Journal of Translational Medicine, 2025 • January 8, 2025
The study identifies key biomarkers related to ferroptosis and the immune microenvironment after SCI, providing clues for subsequent studies at the transcriptional and single-cell levels. WGCNA identi...
KEY FINDING: A novel subcluster of microglia exhibiting M1 polarization and a ferroptosis phenotype is involved in SCI, potentially triggering neuroinflammation and neuronal degeneration.