Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 241-250 of 12,052 results
Muscle & Nerve, 2025 • January 12, 2025
This study evaluated muscle morphology changes in upper limb muscles of individuals with cervical spinal cord injury (cSCI) using ultrasound and compared them to healthy controls (HC). The results sho...
KEY FINDING: Forearm and hand muscle size were significantly lower (15%-41%) in individuals with cSCI compared to healthy controls.
Cellular and Molecular Neurobiology, 2025 • January 12, 2025
This study investigates changes in neuronal activation along the sensory neuroaxis in a rat model of spinal cord injury (SCI) exhibiting below-level pain. The findings reveal that SCI amplifies the en...
KEY FINDING: Spinal cord injury (SCI) amplifies the activation of dorsal horn (DH) neurons in a stimulus-dependent manner, primarily after noxious stimulation.
European Journal of Trauma and Emergency Surgery, 2025 • January 11, 2025
This study investigates the use of periosteal flaps (PF) to enhance bone healing in non-unions, comparing a vascularized (pedicled) PF to a ligated PF and a control group in a rat femur model. The res...
KEY FINDING: The pedicled periosteal flap (PF) group showed a significantly higher bone volume compared to the other groups after 10 weeks.
Journal of Materials Science: Materials in Medicine, 2025 • January 10, 2025
This study investigated the therapeutic effects of plasma-synthesized polypyrrole/iodine (PPy/I) biopolymer in Rhesus monkeys with complete spinal cord transection (SCT), comparing an experimental gro...
KEY FINDING: Plasma-synthesized PPy/I reduced the levels of pro-inflammatory cytokines in the experimental NHP compared to the control NHP after spinal cord transection.
Advanced Science, 2025 • January 10, 2025
This study introduces a single-component hydrogel based on the recombinant protein CsgA, enhanced with the GHK peptide, for spinal cord injury (SCI) repair. The hydrogel's formation relies on the phys...
KEY FINDING: CsgA-GHK hydrogel modulates microglial M2 polarization in vitro, indicating an anti-inflammatory effect.
bioRxiv, 2025 • January 10, 2025
This study investigates how the spinal cord develops, focusing on the intermediate neural progenitors, using zebrafish to investigate the neural plate. The neural plate is pre-patterned by signals lik...
KEY FINDING: The neural plate is patterned by transcription factors, creating distinct states in response to signals like FGF and Wnt, partitioning the tissue into distinct states.
Cureus, 2025 • January 10, 2025
This study assessed microcirculatory changes in cervical SCI patients with neurogenic shock using NIRS and VOT, finding a high prevalence of microcirculatory alterations. The study linked these microc...
KEY FINDING: The prevalence of microcirculatory alterations was high (92%) in patients with SCI and neurogenic shock, with 47% still exhibiting alterations at day 7.
Surgical Neurology International, 2025 • January 10, 2025
This paper reports two cases of dural arteriovenous fistulas (DAVFs) of the occipital sinus (OS) that developed after head trauma. These rare vascular malformations pose diagnostic and therapeutic cha...
KEY FINDING: Trauma can be a significant factor in the development of OS DAVFs. Both cases presented involved patients with a history of head trauma prior to the development of the fistula.
Journal of Neuroinflammation, 2025 • January 10, 2025
This study investigated the therapeutic potential of targeting Fidgetin-like 2 (FL2) after spinal cord injury (SCI) in rats. The researchers hypothesized that FL2 knockdown would increase the benefici...
KEY FINDING: SCI significantly increased FL2 expression in the lesion site and rostral to the lesion at 1 day post-injury.
Health Science Reports, 2025 • January 10, 2025
The Persian versions of both the ASDAS and the EASi‐QoL questionnaires were found to be valid and reliable for use in patients with ankylosing spondylitis. The EASi-QoL questionnaire was validated for...
KEY FINDING: The Persian version of the EASi‐QoL questionnaire demonstrated adequate reliability and validity for assessing quality of life in Iranian AS patients.