Psychometric Properties of the Persian Version of the Evaluation of Ankylosing Spondylitis Quality of Life (EASi‐QoL) and Ankylosing Spondylitis Disease Activity Score (ASDAS) Questionnaires: A Cross‐Sectional Study

Health Science Reports, 2025 · DOI: https://doi.org/10.1002/hsr2.70417 · Published: January 10, 2025

Participation Rheumatology Mental Health

Simple Explanation

This study focuses on ankylosing spondylitis (AS), a long-term inflammatory condition affecting the spine and quality of life. The research checks if two questionnaires, EASi-QoL and ASDAS, are reliable and valid for measuring quality of life and disease activity in Persian-speaking AS patients. The Persian versions of these questionnaires are shown to be useful for assessing AS patients in Iran, offering culturally relevant ways to measure their condition.

Study Duration

1 Year

Participants

70 AS patients (EASi-QoL), 39 patients (ASDAS)

Evidence Level

Cross-sectional study

Key Findings

1
The Persian version of the EASi‐QoL questionnaire demonstrated adequate reliability and validity for assessing quality of life in Iranian AS patients.
2
The Persian version of the ASDAS questionnaire also showed sufficient reliability and validity in measuring disease activity among Iranian AS patients.
3
Both questionnaires showed good internal consistency and test-retest reliability, indicating their stability and accuracy in measuring the intended constructs.

Research Summary

The Persian versions of both the ASDAS and the EASi‐QoL questionnaires were found to be valid and reliable for use in patients with ankylosing spondylitis. The EASi-QoL questionnaire was validated for measuring the QoL in patients with AS, focusing on physical function, disease activity, emotional well-being, and social participation. The ASDAS was validated as a tool for assessing disease activity levels, incorporating patient‐reported outcomes and inflammatory markers such as CRP or ESR.

Practical Implications

Clinical Assessment

The Persian versions of EASi-QoL and ASDAS can be used to accurately assess QoL and disease activity in Iranian AS patients in clinical settings.

Research Applications

These validated questionnaires can be utilized in research to study the impact of AS on patients' lives and evaluate the effectiveness of treatments.

Cultural Relevance

The study provides culturally adapted tools, ensuring that assessments are relevant and understandable for Persian-speaking patients.

Study Limitations

1
Cross-sectional design limits the assessment of sensitivity to change over time.
2
Potential diversity in lifestyles among people of different ethnicities and residing in various cities.
3
The small size of the disease activity index in different countries can likely be attributed to its inclusion of fewer questions compared to other domains.

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