Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 181-190 of 12,052 results
Healthcare, 2025 • January 26, 2025
This study investigates the relationship between Pressure Pain Threshold (PPT) and various clinical, cognitive, and motor factors in Spinal Cord Injury (SCI) patients. It uses a cross-sectional analys...
KEY FINDING: Incomplete SCI lesions are linked to increased pain sensitivity (lower PPT), suggesting altered neural processing exacerbates pain responses.
European Journal of Trauma and Emergency Surgery, 2025 • January 25, 2025
This study evaluated the predictive ability of various frailty scores for adverse outcomes in surgically managed isolated traumatic spinal injury (TSI) patients without spinal cord injury. Simpler fra...
KEY FINDING: The 5-mFI and 11-mFI outperformed other scores in predicting in-hospital mortality, any complication, and failure-to-rescue (FTR).
Dermatol Ther (Heidelb), 2025 • January 24, 2025
This study evaluated the rate of infections in patients with psoriasis and spinal cord injuries treated with systemic immunosuppressants over a 5-year period. The results showed that methotrexate was ...
KEY FINDING: Patients with SCI treated with MTX had higher infection rates compared to those treated with biologics.
Acta Neurochirurgica, 2025 • January 24, 2025
This study investigates the effect of surgical timing on perioperative complications in spinal trauma patients. Delayed surgical treatment may be associated with more perioperative complications compa...
KEY FINDING: Delayed surgical treatment is potentially associated with more perioperative complications compared to early surgery in non-SCI patients.
Acta Neurochirurgica, 2025 • January 24, 2025
This study provides a bibliometric analysis of the application of methylprednisolone in spinal cord injury research over the past 50 years. Collaboration between different academic groups in the field...
KEY FINDING: A total of 1,651 articles were identified, and publication numbers showed a consistent annual increase.
Frontiers in Neurology, 2025 • January 24, 2025
This meta-analysis assessed the efficacy of mesenchymal stem cell-derived exosomes (MSC-exos) in treating spinal cord injury (SCI) in rat models, focusing on studies using a contusion model. The study...
KEY FINDING: MSC-exos significantly improved hind limb movement in SCI-affected rats, as indicated by a statistically significant increase in BBB scores compared to controls.
Genome Medicine, 2025 • January 24, 2025
The study investigates the molecular mechanisms behind resistance exercise-induced recovery in incomplete SCI patients and in mice. Multi-omics analyses reveal that resistance exercise modulates the c...
KEY FINDING: Resistance exercise, especially isotonic exercise, improves muscle strength, walking ability, and balance in individuals with incomplete SCI.
Frontiers in Neuroscience, 2025 • January 24, 2025
This study proposes a multimodal fusion method for detecting sitting and standing intentions based on EEG–EMG functional connectivity, utilizing signals recorded prior to movement execution. The resul...
KEY FINDING: The MI-based EEG–EMG network showed the highest decoding performance (94.33%), outperforming both EEG (73.89%) and EMG (89.16%).
Surgical Neurology International, 2025 • January 24, 2025
This retrospective study analyzed the outcomes of ACDF for subaxial cervical spine injuries (SCSI) in a sub-Saharan neurosurgical center over 6 years. It included 81 patients and assessed demographics...
KEY FINDING: ACDF is associated with good outcomes in patients with incomplete spinal cord injury, with a mean recovery rate of 84.75%.
ACS Nano, 2025 • January 24, 2025
The study focuses on engineering extracellular vesicles (EVs) derived from M2 microglia and modified with Angiopep-2 (Ang2) peptide to target spinal cord injury (SCI) sites. Melatonin pretreatment was...
KEY FINDING: Ang2-modified EVs (Ang2-EVs) effectively target the site of spinal cord injury due to increased expression of LRP-1 after SCI.