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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Veterinary Medicine Research

Browse the latest research summaries in the field of veterinary medicine for spinal cord injury patients and caregivers.

Showing 21-30 of 90 results

NeurologySurgeryVeterinary Medicine

Lumbar vertebral canal stenosis due to marked bone overgrowth after routine hemilaminectomy in a dog

Acta Veterinaria Scandinavica, 2023 • August 3, 2023

This case report details a unique occurrence of significant bone overgrowth in a young dog after undergoing a hemilaminectomy, a spinal surgery. The overgrowth resulted in lumbar vertebral canal steno...

KEY FINDING: The case report documents excessive bone overgrowth causing vertebral stenosis following lumbar spinal decompression in a canine patient, which is the first reported case in veterinary literature.

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Spinal Cord InjuryVeterinary MedicineResearch Methodology & Design

Contrasting Experimental Rodent Aftercare With Human Clinical Treatment for Cervical Spinal Cord Injury: Bridging the Translational ‘‘Valley of Death’’

Journal of Neurotrauma, 2023 • December 1, 2023

This review identifies key dissimilarities between clinical and veterinary SCI care protocols, potentially contributing to the translational "Valley of Death." The authors propose modifications to vet...

KEY FINDING: Significant differences exist between clinical care for human SCI patients and veterinary care for experimental animals, particularly in analgesia, anticoagulation, and stress ulcer prophylaxis.

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NeurologyMedical ImagingVeterinary Medicine

Magnetic resonance imaging characteristics of atlanto-axial subluxation in 42 dogs: Analysis of joint cavity size, subluxation distance, and craniocervical junction anomalies

Open Veterinary Journal, 2023 • September 30, 2023

This study investigated the MRI characteristics of atlanto-axial (AA) subluxation in dogs by comparing affected dogs with a control group. The study focused on joint cavity size, subluxation distance,...

KEY FINDING: Dogs with AA subluxation showed a higher likelihood of intramedullary hyperintensity at the compression level.

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Spinal Cord InjuryVeterinary Medicine

Schiff–Sherrington phenomenon in a cat with complete spinal cord transection from traumatic dorsocranial luxation of the second lumbar vertebra

Veterinary Medicine and Science, 2023 • September 1, 2023

This case report details an occurrence of Schiff–Sherrington phenomenon (SSP) in a cat following a motor vehicle accident that resulted in complete spinal cord transection. The cat presented with typi...

KEY FINDING: The cat exhibited symmetrical forelimb extensor rigidity, neck hyperextension, and hindlimb paraplegia within 30 minutes of a motor vehicle accident, indicative of SSP.

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TraumaVeterinary MedicineResearch Methodology & Design

Case report: Traumatic hemorrhagic cervical myelopathy in a dog

Frontiers in Veterinary Science, 2023 • October 5, 2023

This case report describes a 1.5-year-old French bulldog with traumatic hemorrhagic cervical myelopathy following a road traffic accident. MRI revealed an intramedullary lesion at C2, and conservative...

KEY FINDING: MRI was crucial in diagnosing traumatic hemorrhagic myelopathy in the cervical spinal cord of the dog without vertebral fractures or luxation.

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PharmacologySurgeryVeterinary Medicine

Histopathological and immunohistochemical investigation of the effect of Shilajit in rats with experimental spinal cord injury

Ulus Travma Acil Cerrahi Derg, 2023 • December 1, 2023

This study investigates the potential of Shilajit to mitigate secondary damage in spinal cord injury (SCI) using a rat model. Rats were divided into control, low-dose Shilajit, and high-dose Shilajit ...

KEY FINDING: Histopathological examination showed that the high-dose Shilajit group had lower amounts of morphological damage compared to the low-dose and control groups.

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Regenerative MedicineNeurologyVeterinary Medicine

Combined laser‑activated SVF and PRP remodeled spinal sclerosis via activation of Olig‑2, MBP, and neurotrophic factors and inhibition of BAX and GFAP

Scientific Reports, 2024 • February 2, 2024

This study investigated the combined therapeutic effects of laser-activated stromal vascular fraction (SVF) and platelet-rich plasma (PRP) on spinal cord injury in a feline model of multiple sclerosis...

KEY FINDING: Combining SVF and PRP reduced lesion intensity on MRI scans and improved the physical condition of the cats.

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Spinal Cord InjuryNeurologyVeterinary Medicine

Randomized Controlled Trial of Durotomy as an Adjunct to Routine Decompressive Surgery for Dogs With Severe Acute Spinal Cord Injury

Neurotrauma Reports, 2024 • January 1, 2024

This randomized controlled trial evaluated the effectiveness of durotomy as an adjunct to traditional decompressive surgery for severe acute thoracolumbar spinal cord injury (SCI) in dogs. The study f...

KEY FINDING: Durotomy did not improve the rate of ambulation recovery in dogs with severe acute thoracolumbar SCI compared to traditional decompressive surgery alone.

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Spinal Cord InjuryRegenerative MedicineVeterinary Medicine

Immediate administration of hTERT-MSCs-IDO1-EVs reduces hypoalbuminemia after spinal cord injury

Veterinary Research Forum, 2024 • January 15, 2024

This study investigates the effect of extra-cellular vesicles (EVs) from immortalized human adipose tissue-derived mesenchymal stem cells (hTERT-MSCs) equipped with the ectopic expression of the human...

KEY FINDING: The level of serum albumin in the animals that received IDO1-EVs was increased compared to the SCI group, suggesting a reduction in hypoalbuminemia.

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Regenerative MedicineVeterinary Medicine

Current Advances in Mesenchymal Stem Cell Therapies Applied to Wounds and Skin, Eye, and Neuromuscular Diseases in Companion Animals

Animals, 2024 • April 30, 2024

Mesenchymal stem cells (MSCs) are a promising tool in cell therapies and regenerative medicine because they are easy to obtain and can differentiate into different cell types. MSC-based therapies have...

KEY FINDING: MSC-based therapies have shown promising results in pathologies like spinal cord injuries, wounds, and skin and eye diseases.

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